现代检验医学杂志2024，Vol.39Issue(3)：189-193,5.DOI:10.3969/j.issn.1671-7414.2024.03.032
子宫腺肌病患者外周血红细胞分布宽度水平检测的临床诊断价值研究
Clinical Diagnostic Value of Red Blood Cell Distribution Width in Peripheral Blood of Adenomyosis Patients
摘要
Abstract
Objective To investigate the changes and clinical significance of red blood cell distribution width(RDW)in peripheral blood of patients with adenomyosis.Methods A retrospective study was performed on 300 adenomyosis patients and 250 age-matched individuals who were admitted to the Maternal & Child Health Hospital of Guangxi Zhuang Autonomous Region from January 2020 to December 2022.Mann-Whitney U test was used to compare blood parameters between the patient group(including before and after treatment)and the healthy control group.The diagnostic efficacy of RDW in adenomyosis was evaluated by ROC.Spearman correlation method was used to analyze RDW's association with other blood inflammatory parameters.Logistic multivariate analysis was applied to analyze the independent risk factors for adenomyosis.Results Compared with healthy control group,RDW values were in patients with adenomyosis[14.60％(13.20％～18.65％)vs 13.00％(12.40％～13.80)％],and the difference was statistically significant(Z=11.396,P=0.001).In addition,the RDW levels of patients after treatment were reduced compared with healthy control group[14.10％(12.10％～15.90％)vs 14.60％(13.20％～18.65％)],and the difference was statistically significant(Z=8.339,P=0.001).Correlation analysis results showed that RDW was negatively correlated with hemoglobin,hematocrit,mean corpuscular volume and absolute lymphocyte count(r=-0.709,-0.614,-0.801,-0.131,all P＜0.05),but positively correlated with red blood cell,platelet and platelet lymphocyte ratio(r=0.184,0.439,0.406,all P＜0.05).ROC curve analysis showed that the sensitivity and specificity of RDW for diagnosing adenomyosis were 63.0％and 97.6％,the area under the curve was 0.782,95％confidence interval was 0.745～0.819,respectively.Logistic regression analysis showed that RDW was independently associated with adenomyosis(OR=0.755,95％CI=0.677～1.347,P=0.012).Conclusion RDW was elevated in patients with adenomyosis,suggesting that RDW may be a potential auxiliary diagnostic marker for adenomyosis.关键词
子宫腺肌病/红细胞分布宽度Key words
adenomyosis/red blood cell distribution width分类
医药卫生引用本文复制引用
张玲玲,张雪花,张苑艳,周晖登..子宫腺肌病患者外周血红细胞分布宽度水平检测的临床诊断价值研究[J].现代检验医学杂志,2024,39(3):189-193,5.基金项目
广西自筹经费科研课题(Z20210374) （Z20210374）
广西临床重点专科(医学检验)建设项目. （医学检验）
