阻塞性睡眠呼吸暂停综合征患者认知障碍的研究进展OACSTPCD
Research advances in cognitive impairment in patients with obstructive sleep apnea syndrome
阻塞性睡眠呼吸暂停综合征(OSAS)主要通过慢性间歇性缺氧、睡眠结构紊乱以及分子生物学改变等机制导致认知障碍的发生.其认知障碍主要表现为记忆力、注意力、执行力等下降,并伴有日常生活活动能力的缺损.随着近年对OSAS监测和评估体系的逐渐成熟,针对OSAS治疗手段的研究已取得一定进展,但OSAS导致认知障碍的机制尚需进一步的研究证实.本文就OSAS认知功能障碍近年的研究进展予以综述.
Obstructive sleep apnea syndrome(OSAS)causes cognitive impairment mainly through mechanisms such as chronic intermittent hypoxia,sleep structural disorders,and molecular biological changes.The cognitive impair-ment mainly manifests as reduced memory,attention,and execution abilities,accompanied by a deficiency in daily life ac-tivities.With the gradual maturity of the monitoring and evaluation system for OSAS in recent years,research on treatment methods for OSAS has made some progress,but the mechanism of cognitive impairment caused by OSAS still needs further investigation and confirmation.This article reviews the research progress of cognitive impairment in OSAS in recent years.
王晓;王蕾
山东中医药大学,山东 济南 250000山东中医药大学第二附属医院神经内科,山东 济南 250000
临床医学
阻塞性睡眠呼吸暂停综合征认知障碍肠道菌群脐带血干细胞治疗
Obstructive sleep apnea syndromeCognitive impairmentIntestinal floraCord blood stem cell therapy
《中风与神经疾病杂志》 2024 (005)
436-439 / 4
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