中国老年保健医学2024，Vol.22Issue(2)：139-142,4.DOI:10.3969/j.issn.1672-2671.2024.02.031
1例罗沙司他药物不良反应病例报告并相关文献复习
A clinical report of Roxadustat related adverse drug reactions and literature review
杨晓丽 1王磊 1范勇霞 1平金超2
作者信息
- 1. 北京市昌平区医院肾病学科 102200
- 2. 北京市昌平区医院血液透析中心 102200
- 折叠
摘要
Abstract
Objective To investigate the safety of Roxadustat on anemia to improve understanding of its adverse drug reactions.Methods Clinical data of a patient with dialysis-dependent chronic kidney disease(DD-CKD)and renal anemia who were treated with Roxadustat and experienced treatment-emergent adverse events was retrospectively analyzed,and related literature was reviewed.Results After treated with Roxadustat,the patient has severe symptoms of diarrhea,nausea,and vomiting,and laboratory tests indi-cated concurrent liver failure.After admission,continuous renal replacement therapy(CRRT),protecting liver function,anti-infec-tion,and other treatments were given to the patient.The patient's symptoms and laboratory results gradually improved,and ultimately the patient was discharged from the hospital.Conclusion As a novel oral medication for the renal anemia,further researches are needed on the adverse drug reactions with Roxadustat,we need to strengthen the understanding of its adverse drug reactions during the use of Roxadustat.关键词
低氧诱导因子脯氨酰羟化酶抑制剂/罗沙司他/不良反应/血液透析/肾性贫血Key words
hypoxia-inducible factor prolyl hydroxylase inhibitor(HIF-PHI)/Roxadustat/renal anemia/adverse drug reactions/renal dialysis引用本文复制引用
杨晓丽,王磊,范勇霞,平金超..1例罗沙司他药物不良反应病例报告并相关文献复习[J].中国老年保健医学,2024,22(2):139-142,4.
