中国临床药理学杂志2024，Vol.40Issue(10)：1525-1529,5.DOI:10.13699/j.cnki.1001-6821.2024.10.028
硫氧还蛋白-1在脑缺血中作用的研究现状
Research status of research on the role of thioredoxin 1 in cerebral ischemia
摘要
Abstract
Thioredoxin-1(Trx-1)is a petite redox protein primarily encountered in mammalian cells.It responds to alterations in the redox environment by facilitating electron transfer and regulating associated proteins.This paper provides a concise overview of Trx-1,focusing on its altered expression patterns during cerebral ischemia.The emphasis is on its neuroprotective attributes following cerebral ischemia,encompassing anti-oxidation,anti-inflammation,anti-apoptosis,promotion of cell growth,angiogenesis,and its involvement in cerebral ischemia-related pathologies.关键词
硫氧还蛋白-1/脑缺血/硫氧还蛋白相互作用蛋白/神经保护/作用机制Key words
thioredoxin-1/cerebral ischemia/thioredoxin interacting protein/neuroprotection/mechanism of action分类
医药卫生引用本文复制引用
刘怀玉,王可,闫文静,王月,张文欣,何治..硫氧还蛋白-1在脑缺血中作用的研究现状[J].中国临床药理学杂志,2024,40(10):1525-1529,5.基金项目
国家自然科学基金面上基金资助项目(82204837) （82204837）
国家自然科学基金青年科学基金资助项目(82073824) （82073824）
浙江省自然科学基金资助项目(LQ23H290004) （LQ23H290004）
