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脾虚证实验动物模型构建及评价方法的研究述评

张永龙 郭义 李忠正 马唯刚 钱星羽 赵素红 李姗姗 郭永明 徐枝芳 潘兴芳 邱继文

中国实验动物学报2024,Vol.32Issue(3):385-396,12.
中国实验动物学报2024,Vol.32Issue(3):385-396,12.DOI:10.3969/j.issn.1005-4847.2024.03.013

脾虚证实验动物模型构建及评价方法的研究述评

Construction of experimental animal models and evaluation of spleen deficiency syndrome:a review

张永龙 1郭义 2李忠正 3马唯刚 1钱星羽 1赵素红 1李姗姗 1郭永明 3徐枝芳 3潘兴芳 3邱继文4

作者信息

  • 1. 天津中医药大学实验针灸学研究中心,天津 301617
  • 2. 天津中医药大学实验针灸学研究中心,天津 301617||天津中医药大学,天津 301617
  • 3. 天津中医药大学实验针灸学研究中心,天津 301617||天津中医药大学针灸推拿学院,天津 301617
  • 4. 天津中医药大学实验针灸学研究中心,天津 301617||天津中医药大学医学技术学院,天津 301617
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摘要

Abstract

The construction of experimental animal models plays an important supporting role in research into the mechanisms of action of Chinese medicines.There have been increasing reports of the construction and evaluation of animal models of spleen deficiency;however,the construction method have involved different standards and there has been insufficient objectification of the evaluation indexes.In this review,we summarize the construction and evaluation method of animal models of spleen deficiency from the aspects of animal selection,model establishment,macroscopic characterization,behavioral experiments,and objective indexes of spleen deficiency,with a view to providing theoretical guidance for the construction of experimental animal models of spleen deficiency and references for the selection of animal model platforms for spleen deficiency.

关键词

脾虚证/动物模型/评价方法/综述

Key words

spleen deficiency/animal models/evaluation methods/review

分类

生物科学

引用本文复制引用

张永龙,郭义,李忠正,马唯刚,钱星羽,赵素红,李姗姗,郭永明,徐枝芳,潘兴芳,邱继文..脾虚证实验动物模型构建及评价方法的研究述评[J].中国实验动物学报,2024,32(3):385-396,12.

基金项目

国家自然科学基金面上项目(82174524). Funded by the National Natural Science Foundation of China General Program(82174524). (82174524)

中国实验动物学报

OA北大核心CSTPCD

1005-4847

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