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四物汤的药理作用研究进展

周大果 沈子芯 牟春燕 朱路文

中医药信息2024,Vol.41Issue(5):69-75,7.
中医药信息2024,Vol.41Issue(5):69-75,7.DOI:10.19656/j.cnki.1002-2406.20240512

四物汤的药理作用研究进展

Research Progress on Pharmacological Effects of Siwu Decoction

周大果 1沈子芯 1牟春燕 1朱路文1

作者信息

  • 1. 黑龙江中医药大学,黑龙江 哈尔滨 150040
  • 折叠

摘要

Abstract

Siwu Decoction is a basic formula for nourishing and regulating blood,with the characteristics of nourishing blood without stagnation and moving blood without damaging it.It is used to treat various clinical diseases and has high clinical value.The authors found through reviewing relevant research literature that this formula has pharmacological effects such as supplementing blood volume,promoting blood circulation and anticoagulation,estrogen like effects,bidirectional regulation of the uterus,improving ovarian function,lowering blood lipids,enhancing learning and memory ability,antioxidant damage,anti-inflammatory and antibacterial,enhancing immune function,anti-aging,liver protection and radiation resistance,drug damage and anti-mutation.It mainly acts on the blood system,female reproductive system,and cardiovascular and cerebrovascular systems.The therapeutic effects are mainly achieved through phosphatidylinositol-3-kinase/protein kinase B(PI3K/Akt)signaling pathway,epidermal growth factor receptor/phosphatidylinositol-3-kinase(EGFR/PI3K)signaling pathway,liver kinase B1/adenylate activated protein kinase(LKB1/AMPK)signaling pathway,etc.

关键词

四物汤/药理作用/研究进展

Key words

Siwu Decoction/Pharmacological effects/Research progress

引用本文复制引用

周大果,沈子芯,牟春燕,朱路文..四物汤的药理作用研究进展[J].中医药信息,2024,41(5):69-75,7.

基金项目

国家自然科学基金项目(82174477) (82174477)

中医药信息

1002-2406

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