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A matrix metalloproteinase-responsive hydrogel system controls angiogenic peptide release for repair of cerebral ischemia/reperfusion injury

Qi Liu Jianye Xie Runxue Zhou Jin Deng Weihong Nie Shuwei Sun Haiping Wang Chunying Shi

Neural Regeneration Research2025，Vol.20Issue(2)：P.503-517,15.

Neural Regeneration Research2025，Vol.20Issue(2)：P.503-517,15.DOI:10.4103/NRR.NRR-D-23-01322

A matrix metalloproteinase-responsive hydrogel system controls angiogenic peptide release for repair of cerebral ischemia/reperfusion injury

Qi Liu ¹Jianye Xie ²Runxue Zhou ³Jin Deng ¹Weihong Nie ³Shuwei Sun ³Haiping Wang ⁴Chunying Shi³

作者信息

1. Department of Human Anatomy,Histology and Embryology,School of Basic Medicine,Qingdao University,Qingdao,Shandong Province,China Department of Neurology,The Affiliated Hospital of Qingdao University,Qingdao,Shandong Province,China
2. Department of General Practice,The Affiliated Hospital of Qingdao University,Qingdao,Shandong Province,China
3. Department of Human Anatomy,Histology and Embryology,School of Basic Medicine,Qingdao University,Qingdao,Shandong Province,China
4. Department of Neurology,The Affiliated Hospital of Qingdao University,Qingdao,Shandong Province,China
折叠

摘要

关键词

angiogenesis/biomaterial/blood-brain barrier/cerebral ischemia/reperfusion injury/control release/drug delivery/inflammation/QK peptides/matrix metalloproteinase-2/neuroprotection/self-assembling nanofiber hydrogel

分类

医药卫生

引用本文复制引用

Qi Liu,Jianye Xie,Runxue Zhou,Jin Deng,Weihong Nie,Shuwei Sun,Haiping Wang,Chunying Shi..A matrix metalloproteinase-responsive hydrogel system controls angiogenic peptide release for repair of cerebral ischemia/reperfusion injury[J].Neural Regeneration Research,2025,20(2):P.503-517,15.

基金项目

supported by the Natural Science Foundation of Shandong Province,No.ZR2023MC168 （）

the National Natural Science Foundation of China,No.31670989 （）

the Key R&D Program of Shandong Province,No.2019GSF107037(all to CS). （all to CS）

Neural Regeneration Research

ISSN：1673-5374

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