口腔疾病防治2024，Vol.32Issue(8)：640-645,6.DOI:10.12016/j.issn.2096-1456.2024.08.010
牙釉质发育不全诊疗策略的研究现状
Status of research on diagnostic and treatment strategies for enamel hypoplasia
摘要
Abstract
Enamel hypoplasia is a disease that results in enamel formation and mineralization abnormalities due to the effects of hereditary or environmental variables during tooth development.Affected teeth may appear to have an ab-errant color and structural flaws.Patients often display clinical signs such as tooth defects,tooth sensitivity,and tooth discoloration.The disease can cause patients to feel physically and mentally uncomfortable and negatively impact their ability to chew,swallow,speak,and smile.In this review,the pathophysiology of enamel hypoplasia,which is caused by anomalies in gene regulation and changes in environmental variables,is summarized,along with a list of clinical diag-nostic indicators based on the most commonly used disease classifications.The main points are as follows:① enamel hypoplasia changes only the color and transparency of the affected teeth;② lesions often occur symmetrically in groups;③ the age at which systemic diseases or nutritional disorders occur during tooth development can be predicted based on the patient's impaired teeth;and ④ banded or pitted brown depression on the enamel surface can easily be confused with dental fluorosis.It also elaborates on the comprehensive application of tooth bleaching,desensitization,direct or in-direct restoration and other treatment modalities according to unique chief complaints by different patients and suggests the use of multidisciplinary cooperative sequential treatment for critical infants and young children.The goal of this re-view is to provide professionals with the most recent information and advice about enamel hypoplasis.Current literature on this condition is primarily case reports.To further standardize the diagnostic and management approaches for this dis-ease,additional high-quality clinical research and systematic reviews are required.关键词
牙釉质发育不全/牙釉质矿化不全/牙釉质成熟不全/遗传性釉质发育不全/发病机制/临床诊断/治疗策略/序列治疗Key words
enamel hypoplasia/enamel hypocalicific/enamel hypomaturation/amelogenesis imperfecta/pathogenesis/clinical diagnosis/treatment strategy/sequential treatment分类
医药卫生引用本文复制引用
唐权,杨俊义,程磊..牙釉质发育不全诊疗策略的研究现状[J].口腔疾病防治,2024,32(8):640-645,6.基金项目
国家自然科学基金面上项目(82071106) This study was supported by the grants from National Natural Science Foundation of China(No.82071106). （82071106）
