寒旱农业科学2024，Vol.3Issue(5)：457-462,6.DOI:10.3969/j.issn.2097-2172.2024.05.013
口服麻杏石甘散对BRD犊牦牛血清指标的影响
Effects of Oral Administration Maxingshigan Powder on Serum Indexes of BRD Yak Calves
摘要
Abstract
This study investigated the therapeutic effects of Maxingshigan powder on bovine respiratory disease(BRD)and its effects on serum oxidative stress indexes and inflammatory indexes,so as to provide a theoretical basis for clinical application.12 yak calves with BRD symptoms were selected and given Maxingshigan powder at 0.75 g/kg dose in warm water once a day for 6 days,and 5 healthy calves were fed normally as the control.On the 0,3 and 6 days of medication,the clinical symptoms of yak calves were recorded and scored according to WI scoring table,and blood was collected from jugular vein.The serum levels of tumor necrosis factor-α(TNF-α),lysozyme(LYZ),interleukin-6(IL-6),lactoferrin(LTF)and serum amyloid A(SAA)were determined after centrifugation.Results showed that WI score on the 6th day after medication was significantly lower than that on the 3rd day(P<0.05),the cure rate was 83.3%on the 6th day after medication.After 6 days of treatment,the serum concentrations about anti-inflammatory and antioxidant indexes of TNF-α,LZM,IL-6,LTF,SAA in sick group were not significantly different from those in healthy group(P＞0.05).In conclusion,Maxingshigan powder can effectively improve the BRD symptoms of yak calves,relieve the inflammatory response and oxidative stress symptoms,and has certain reference value for the treatment of BRD in yaks.This method is suitable for the treatment of respiratory diseases in yaks and related herbivores in alpine area.关键词
BRD/犊牦牛/麻杏石甘散/氧化应激指标Key words
BRD/Yak calf/Maxingshigan powder/Oxidative stress index分类
农业科技引用本文复制引用
陈平,何振富,谢建鹏,王斐,庞宝梅,杜海科,马学军..口服麻杏石甘散对BRD犊牦牛血清指标的影响[J].寒旱农业科学,2024,3(5):457-462,6.基金项目
甘肃省科协2020年甘肃省青年科技人才托举工程(2020-05) （2020-05）
甘肃省农业科学院农业科技自主创新专项博士基金项目(2021GAAS51) （2021GAAS51）
甘肃省科协2023年创新驱动助力工程项目(GXH20230817-9) （GXH20230817-9）
甘肃省科技厅2021年度"三区"人才支持计划科技人员专项计划. （）
