肝移植治疗慢加急性肝衰竭的临床实践细节OACSTPCD
Clinical practice details of liver transplantation for the treatment of acute-on-chronic liver failure
慢加急性肝衰竭(ACLF)患者病情发展迅速,常伴多器官衰竭,预后较差.肝移植在ACLF患者治疗中发挥重要作用,但治疗过程中仍有多种风险导致术后患者死亡.本文就ACLF的原发病治疗、病情评估、手术时机选择、桥接治疗、供肝选择、手术特点、术后免疫抑制剂应用等临床实践进行探讨,为优化ACLF患者的肝移植治疗提供新方向.
Patients with acute-on-chronic liver failure(ACLF)develop rapidly,are often concomitant multiple organ failure,and have a poor prognosis.Liver transplantation plays a crucial role in the treatment of ACLF patients;however,there are still multiple risks associated to patients'postoperative death during treatment.In this paper,clinical practice concerning primary disease treatment,disease evaluation,operation time selection,bridging therapy,donor liver selection,surgical characteristics,postoperative application of immunosuppresant of ACLF is explored,aiming at providing novel direction for optimizing liver transplantation therapy in ACLF patients.
陈军泽;张诚;董昆;董淳强
广西医科大学第一附属医院器官移植科,广西南宁市 530021
临床医学
慢加急性肝衰竭肝移植原发疾病免疫抑制预后
Acute-on-chronic liver failureLiver transplantationPrimary diseaseImmunosuppresantPrognosis
《广西医学》 2024 (003)
333-339 / 7
区域性高发肿瘤早期防治研究教育部/广西重点实验室自主研究课题(GKE-ZZ202142,GKE-ZZ202115)
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