广西医学2024，Vol.46Issue(3)：340-346,7.DOI:10.11675/j.issn.0253-4304.2024.03.03
免疫检查点抑制剂在肝癌肝移植中的应用进展
Application progress of immune checkpoint inhibitors in liver transplantation for liver cancer
摘要
Abstract
Immune checkpoint inhibitors(ICIs)has opened a new chapter in the treatment of liver cancer and has become one of the main options for liver cancer transformation and adjuvant therapy.At present,ICIs has been widely used in the down-staging treatment of liver cancer before liver transplantation,and some exploratory applications have also been made in the treatment of liver cancer recurrence and metastasis after liver transplantation.However,due to the potential risk of rejection reactions induced by ICIs,there are still many doubts and problems in the application of ICIs before and after liver transplantation for liver cancer.In this paper,research reports related to this field domestic and overseas in recent years are comprehensively analyzed,aiming at providing references for the reasonable,safe and effective application of ICIs before and after liver transplantation.关键词
肝癌/肝移植/免疫检查点抑制剂/综述Key words
Liver cancer/Liver transplantation/Immune checkpoint inhibitors/Review分类
医药卫生引用本文复制引用
张全保,王正昕..免疫检查点抑制剂在肝癌肝移植中的应用进展[J].广西医学,2024,46(3):340-346,7.基金项目
国家重点研发计划项目(2023YFC2505900) （2023YFC2505900）
国家自然科学基金(82241225,81873874,82071797) （82241225,81873874,82071797）
