急性白血病患者癌症复发恐惧的潜在类别及影响因素OACSTPCD
Potential category and influencing factors of fear for cancer recurrence in patients with acute leukemia
目的 了解急性白血病患者癌症复发恐惧的潜在类别,并探讨其影响因素.方法 选取130例急性白血病患者作为研究对象,采用自行设计的一般资料调查表及恐惧疾病进展简化问卷(FoP-Q-SF)、医院焦虑抑郁量表(HADS)、领悟社会支持量表(PSSS)对其进行调查.运用Mplus 8.3软件进行潜在剖面分析,根据潜在剖面分析结果将患者进行分组.采用多因素Logistic回归模型分析急性白血病患者癌症复发恐惧的影响因素.结果 急性白血病患者的FoP-Q-SF 总分为(31.55±10.62)分,其中52例(40.0%)患者的总分≥34分,而患者的PSSS 总分、HADS 总分分别为(66.95±10.77)分、(13.10±7.28)分.潜在剖面分析结果显示2个潜在类别的模型拟合结果最好,根据潜在类别将患者分为心理功能失调组(n=51)和心理状态良好组(n=79).多因素Logistic回归分析结果显示,HADS总分及PSSS总分是急性白血病患者癌症复发恐惧的影响因素(P<0.05).结论 急性白血病患者的癌症复发恐惧处于中等水平,且存在明显的分类特征.社会支持水平低和处于焦虑/抑郁状态的急性白血病患者发生癌症复发恐惧的风险较高.
Objective To understand the potential category of fear for cancer recurrence in patients with acute leukemia,and to explore its influencing factors.Methods A total of 130 patients with acute leukemia were selected as the research subjects.The self-designed general data inventory,Fear of Progression Questionnaire-Short Form(FoP-Q-SF),Hospital Anxiety and Depression Scale(HADS),and Perceived Social Support Scale(PSSS)were used to investigate on the research subjects.The Mplus 8.3 software was used to perform potential profile analysis,and patients were assigned to groups according to the results of potential profile analysis.The influencing factors for cancer recurrence fear in patients with acute leukemia were analyzed by employing the multivariate Logistic regression model.Results The total score of FoP-Q-SF in patients with acute leukemia was 31.55±10.62,therein the total score of 52 patients(40.0%)was≥34,whereas the total scores of PSSS and HADS in patients were 66.95±10.77 and 13.10±7.28,respectively.The results of potential profile analysis revealed that the best model fitting result was obtained from two potential categories,and patients were assigned to psychological dysfunction group(n=51)or favorable mental state group(n=79)according to the potential category.The results of multivariate Logistic regression analysis indicated that the total scores of HADS and PSSS were the influencing factors for cancer recurrence fear in patients with acute leukemia(P<0.05).Conclusion Fear for cancer recurrence in patients with acute leukemia is at the medium level,and there are obvious classification features.Acute leukemia patients with low level of social support and anxiety/depression status are at relatively high risk of fear for cancer recurrence.
张小芳;陈国连;钟博华;陈莹莹;黄钰清
广西医科大学第一附属医院 肿瘤内科,广西南宁市 530021广西医科大学第一附属医院 重症医学科,广西南宁市 530021
临床医学
急性白血病癌症复发恐惧潜在剖面分析潜在类别影响因素焦虑抑郁社会支持
Acute leukemiaFear for cancer recurrencePotential profile analysisPotential categoryInfluencing factorsAnxietyDepressionSocial support
《广西医学》 2024 (003)
382-387 / 6
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20201475)
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