广州医药2024,Vol.55Issue(4):382-387,6.DOI:10.3969/j.issn.1000-8535.2024.04.008
重复经颅磁刺激应用于帕金森病失眠患者中的效果及对睡眠质量的影响研究
Effect of repetitive transcranial magnetic stimulation on Parkinson's patients with insomnia and its influence on sleep quality
黄大帅 1朱新臣 1王延庆1
作者信息
- 1. 南阳南石医院神经内科一病区(河南南阳 473000)
- 折叠
摘要
Abstract
Objective To investigate the effect of repetitive transcranial magnetic stimulation(rTMS)on Parkinson's insomnia and its influence on sleep quality.Methods A total of 100 Parkinson's patients with insomnia admitted to the Department of Neurology,Nanyang Nanshi Hospital from January 2021 to March 2022 were selected and divided into the reference group(n=50)and the study group(n=50)according to random number table method.The reference group was treated with conventional western medicine,and the study group was treated with rTMS on the basis of the reference group.The levels of neurotransmitters,symptoms of Parkinson's disease and sleep quality were compared.Results The effective rate of the study group was 98.00%(49/50),which was higher than 82.00%(41/50)of the reference group,with statistical significance(P<0.05).After treatment,the levels of dopamine and 5-hydroxytryptamine in the study group,(6.84±0.62)and(22.75±0.59),were higher than those in the reference group,and the comparison was statistically significant(P<0.05).After treatment,the total score of Parkinson's symptom and sleep quality in the study group were lower than those in the reference group,with statistical significance(P<0.05).Conclusions The application of rTMS in the treatment of Parkinson's patients with insomnia can improve the curative effect,significantly improve the sleep quality and symptoms of Parkinson's disease,and is worthy of further application and promotion.关键词
重复经颅磁刺激/帕金森/失眠/睡眠质量Key words
repetitive transcranial magnetic stimulation/Parkinson's disease/insomnia/sleep quality引用本文复制引用
黄大帅,朱新臣,王延庆..重复经颅磁刺激应用于帕金森病失眠患者中的效果及对睡眠质量的影响研究[J].广州医药,2024,55(4):382-387,6.