中医学报2024,Vol.39Issue(6):1295-1300,6.DOI:10.16368/j.issn.1674-8999.2024.06.217
AHP-熵权法结合正交试验优化三化汤的提取工艺
Optimized Extraction Process of Sanhua Decoction with AHP-entropy Weight Method Combined with Orthogonal Test
摘要
Abstract
Objective:To optimize the extraction process of Sanhua Decoction.Methods:The extraction process of Sanhua Decoction was optimized by taking the grinding particle size,water amount added and decoction power as the investigation factors,as well as taking the comprehensive score of the content and extract rate of rhein,emodin,aloe emodin,naringin,hesperidin,magnolol,honokiol and Qiang-huol as the investigation index,combined with orthogonal test.Results:The best extraction process parameters of Sanhua Decoction are as follows:the particles are2.00-4.75 mm(passed4 mesh sieve,but not 10 mesh sieve),and 31 g of each medicine was taken,in addition,the water was 2 400 mL.After boiling over high heat(1 500 W),reduce the heat to 300 W and maintain a slight boil to 1 200 mL.Conclusion:The optimized extraction process of Sanhua Decoction is stable and reliable,which provides a reference for the research and development of its preparation.关键词
三化汤/AHP-熵权法/提取工艺/正交试验Key words
Sanhua Decoction/AHP-entropy weight method/extraction process/orthogonal test分类
医药卫生引用本文复制引用
于红艳,孙婉春,史宏妍,王书莉,张丽敏..AHP-熵权法结合正交试验优化三化汤的提取工艺[J].中医学报,2024,39(6):1295-1300,6.基金项目
河南省中医药科学研究专项项目(2021JDZX2116) (2021JDZX2116)
河南省中医药拔尖人才培养项目{豫卫中医函[2021]15号} ()