中国实用神经疾病杂志2024，Vol.27Issue(5)：547-551,5.DOI:10.12083/SYSJ.231442
基于CTA数据后处理对颈内动脉狭窄处血流动力学特点的研究
Study on the hemodynamic characteristics of internal carotid artery stenosis based on CTA reprocessing
摘要
Abstract
Objective To study the hemodynamic characteristics of internal carotid artery stenosis by establishing a computational fluid dynamics(CFD)simulation model based on CTA image data of head and neck.Methods A retrospective analysis was performed on 30 patients who met the inclusion criteria in the Second Affiliated Hospital of Bengbu Medical College from May 2021 to March 2023.3D craniocerebral vascular reconstruction technology was used to conduct 3D model reconstruction of carotid artery and internal carotid artery,and hemodynamic parameters were analyzed,measured and statistically analyzed.The wall shear stress(WSS),time-average wall shear stress(TAWSS),oscillating shear index(OSI)and relative residence time(RRT)of internal carotid artery stenosis were measured,and the correlation and difference among the parameters were analyzed.Results The WSS,TAWSS,OSI and RRT in the narrow area of internal carotid artery were 58.6693(43.8820,65.9792),18.6958(14.9738,25.5346),0.0746(0.0633,0.0854),0.0923(0.0822,0.1096),respectively.WSS,TAWSS,OSI and RRT on the normal side were 15.2153(9.0397,25.1172),5.1382(3.3734,6.1399),0.1227(0.0997,0.1512),0.7123(0.5190,0.8217),respectively.In addition,the blood flow velocity and blood flow of the narrow internal carotid artery were 1.9259±0.1255 and 4.3741±0.2779,respectively,and the blood flow velocity and blood flow of the normal side were 0.9926±0.0747 and 6.1907±0.2609,respectively.WSS and TAWSS in the stenosis area were significantly increased,while OSI and RRT were relatively small,and the blood flow velocity was significantly increased,accompanied by a small blood flow,with statistical significance(P<0.05).Conclusion Compared with normal side,the hemodynamic factors of internal carotid artery stenosis were significantly changed.CFD simulation analysis method can be used to evaluate the degree of changes in hemodynamic factors to help analyzing the risk degree of patients with internal carotid artery stenosis,and assist clinical diagnosis,treatment and prognosis assessment.关键词
颈内动脉狭窄/CT血管造影/头颈部/计算流体力学/血流动力学Key words
Internal carotid artery stenosis/CT angiography(CTA)/Head and neck/Computational fluid dynamics/Hemodynamics分类
医药卫生引用本文复制引用
孙玉玺,程哲,陈硕硕,巢青,束汉生..基于CTA数据后处理对颈内动脉狭窄处血流动力学特点的研究[J].中国实用神经疾病杂志,2024,27(5):547-551,5.基金项目
安徽省高等教育厅重点项目(编号:2022AH051423) （编号:2022AH051423）
安徽省高等教育厅重点项目(编号:2022AH051507) （编号:2022AH051507）
蚌埠医学院研究生科研创新项目(编号:Byycx22127) （编号:Byycx22127）
