中国实用神经疾病杂志2024，Vol.27Issue(5)：616-621,6.DOI:10.12083/SYSJ.231514
踝泵训练联合低分子肝素钙治疗脑卒中偏瘫合并下肢深静脉血栓有效性及安全性
Effectiveness and safety of ankle pump training combined with low molecular heparin calcium in the treatment of stroke hemiplegia combined with lower extremity deep vein thrombosis
摘要
Abstract
Objective To investigate the effectiveness and safety of ankle pump training combined with low molecular heparin calcium in the treatment of stroke hemiplegia combined with lower limb deep vein thrombosis.Methods Totally 119 patients with stroke hemiplegia combined with lower limb deep vein thrombosis who were treated in the Affiliated Tongren Hospital of Wuhan University/Wuhan Third Hospital from July 2020 to September 2022 were randomly selected as the study object,and they were divided into the training group of 40 cases and the medication group of 40 cases,and the combined group of 39 cases according to the method of randomized numerical table.Ankle pump training intervention,low molecular weight heparin calcium intervention and combined intervention were given respectively.The efficacy and safety of treatment were analyzed.Blood related indexes,limb function and daily living ability were observed.Results The treatment efficiency of the combined group(92.31%)was significantly higher than that of the training group(75.00%)and the drug group(70.00%,P<0.05).After the intervention,the blood-related indexes of the three groups were significantly decreased(P<0.05),and the fibrinogen(FIB),D-dimer(D-D),plasma viscosity and whole blood viscosity of the combined group were lower than those of the training and drug groups(P<0.05),and the prothrombin time(PT)level was higher than that of the training and drug groups(P<0.05).After intervention,the limb function of the three groups was significantly increased(P<0.05),and the indexes of the combined group were higher than those of the training group and the drug group(P<0.05).After intervention,the ADL score and BI score of the 3 groups were significantly increased(P<0.05),and the indexes of the combined group were higher than those of the training group and the drug group(P<0.05).The incidence of adverse reactions in combination group(2.56%)was significantly lower than that in training group(22.50%)and drug group(22.50%,P<0.05).There was no significant difference between the training group and the drug group(P>0.05).Conclusion Ankle pump training combined with low molecular calcium calcium has high effectiveness in the treatment of hemiplegia combined with lower limb deep vein thrombosis in stroke,which can significantly reduce blood viscosity,improve the coagulation function and limb motor function,and is conducive to improving the quality of life of the patients,and has high safety.关键词
踝泵训练/低分子肝素钙/脑卒中/偏瘫/下肢深静脉血栓/肢体运动功能Key words
Ankle pump training/Low molecular heparin calcium/Stroke/Hemiplegia/Lower extremity deep vein thrombosis/Limb motor function分类
医药卫生引用本文复制引用
李叶子,余平..踝泵训练联合低分子肝素钙治疗脑卒中偏瘫合并下肢深静脉血栓有效性及安全性[J].中国实用神经疾病杂志,2024,27(5):616-621,6.基金项目
武汉市医学科研项目(编号:WX19D22) （编号:WX19D22）
