结核与肺部疾病杂志2024，Vol.5Issue(3)：219-224,6.DOI:10.19983/j.issn.2096-8493.2024067
慢性阻塞性肺疾病症状群及其与患者生活质量的相关性研究
Research of symptom groups of chronic obstructive pulmonary disease and their correlation with patient's quality of life
摘要
Abstract
Objective:To explore the composition of symptom groups at different stages of chronic obstructive pulmonary disease(COPD)patients,the interrelationships between symptom groups,and the correlation between symptom groups and patient's quality of life.Methods:Convenience sampling was used to select 223 COPD patients who were hospitalized from November 2022 to November 2023 in Department of Respiratory and Critical Care Medicine,Ningbo University Affiliated to People's Hospital.A patient basic information questionnaire,memorial symptom assessment scale(MSAS),and COPD assessment test(CAT)were used to evaluate symptoms,breathing difficulties,and emotions of the patients on the first day of hospitalization(T1,disease exacerbation phase),the day before or on the day of discharge(T2),and one month(T3)and three months(T4)after discharge(disease stable phase).Statistical description,factor analysis,and cluster analysis were used to analyze the symptoms and evaluate their impact on the patient's quality of life.Results:The average numbers of symptoms in COPD patients between T1 and T4were 29(26,31),25(22,28),27(25,29),and 29(27,31),respectively.There were three different symptom groups at four time points:respiratory perception related symptom group,psychological perception related symptom group,and gastrointestinal perception related symptom group.The average total scores of CAT scales for COPD patients between T,and T4 were 29.13±6.37,20.31±6.47,18.68±6.27,and 20.31±6.47,respectively,variance analysis showed that the difference was statistically significant(F=126.284,P＜0.001).The correlation analysis between three symptom groups and patient's quality of life showed that except for gastrointestinal perception related symptom group at T4 which was not correlated with the total score of CAT(r=0.009,P＞0.05),all other symptom groups were positively correlated with the total score of CAT(Ps＜0.05).Conclusion:COPD patients experience different symptoms during the acute and stable phases of the disease,with symptoms clustering in three forms and worsening.The more severe the distress on the patient,the greater the impact on their quality of life.关键词
肺疾病,阻塞性/体征和症状/生活质量Key words
Pulmonary disease,obstructive/Signs and symptoms/Quality of life分类
医药卫生引用本文复制引用
邱巧静,陶洋,沈佳妮,徐佳频,朱丽红,顾芬..慢性阻塞性肺疾病症状群及其与患者生活质量的相关性研究[J].结核与肺部疾病杂志,2024,5(3):219-224,6.基金项目
National Natural Science Foundation of China Youth Fund Project(71904144) 国家自然科学基金青年基金项目(71904144) （71904144）
