结核与肺部疾病杂志2024，Vol.5Issue(3)：260-266,7.DOI:10.19983/j.issn.2096-8493.2024082
细胞焦亡与非小细胞肺癌转移相关性的研究进展
Research progress on the correlation between pyroptosis and metastasis of non-small cell lung cancer
昌雨婷 1张欣然 1韩高华1
作者信息
- 1. 南京医科大学附属泰州人民医院肿瘤科,泰州 225300
- 折叠
摘要
Abstract
With the increasing incidence and mortality of non-small cell lung cancer(NSCLC),the focus and challenge of researches have been shifted towards delaying disease progression and prolonging patient survival.Metastasis is an inevitable aspect of tumor development which significantly affects patients'median length of survival.Therefore,predicting metastasis occurrence and conducting preventive treatment are crucial for improving NSCLC prognosis.Some researchers have raised concerns about pyroptosis as a programmed cell death mode that can be expressed in both normal tissue and tumor cells,with distinctive biological effects in different types of tumor.This paper provides a summary of different activation pathways and application values of pyroptosis,focusing on its dual role in NSCLC metastasis.It suggests that pyroptosis may play an important role in targeted metastasis when considering current researches on brain metastasis of non-small cell lung cancer,offering a new approach to study the correlation between cell pyroptosis and NSCLC metastasis.关键词
癌,非小细胞肺/肿瘤转移/研究/细胞焦亡Key words
Carcinoma,non-small-cell lung/Neoplasm metastasis/Research/Pyroptosis分类
医药卫生引用本文复制引用
昌雨婷,张欣然,韩高华..细胞焦亡与非小细胞肺癌转移相关性的研究进展[J].结核与肺部疾病杂志,2024,5(3):260-266,7.
