昆明医科大学学报2024，Vol.45Issue(5)：1-7,7.DOI:10.12259/j.issn.2095-610X.S20240501
DRD1在神经系统疾病和功能中的研究进展
Research Progress of DRD1 in Neurological Disorders and Functions
摘要
Abstract
Dopamine D1 receptor(DRD1)is currently known as the dopamine receptor subtype with the most widespread expression in the nervous system.DRD1 plays a role in various signaling pathways to perform many functions such as movement,emotion,cognition,learning and memory,as well as neuroendocrine activities.These functions may be associated with conditions like Parkinson's syndrome,schizophrenia,depression,and immune responses.Changes in the expression of DRD1 often indicate alterations in neurological functions.Therefore,DRD1 has the potential to serve as an indicator of neurological disorders and functional changes,as well as a potential target for the treatment of neurological diseases.This article reviews the distribution and functions of DRD1 in the nervous system,with a particular emphasis on DRD1's involvement in signaling pathways related to the nervous system.关键词
多巴胺受体/神经系统/DRD1/多巴胺Key words
Dopamine receptor/Nervous system/DRD1/DA分类
医药卫生引用本文复制引用
李瑾瑜,冯良升,高扬,李钰,吴帮旭,邹英鹰..DRD1在神经系统疾病和功能中的研究进展[J].昆明医科大学学报,2024,45(5):1-7,7.基金项目
国家自然科学基金资助项目(32060184) （32060184）
昆明医科大学大学生创新创业训练基金资助项目(2023CXD267) （2023CXD267）
