皮肤性病诊疗学杂志2024，Vol.31Issue(5)：334-339,6.DOI:10.3969/j.issn.1674-8468.2024.05.007
局限性硬皮病诊断技术研究进展
Progress in the diagnostic techniques for localized scleroderma
摘要
Abstract
Localized scleroderma(LS)is an autoimmune disease primarily affecting the skin,subcutaneous fat,and deep tissues,potentially leading to significant functional impairment and aesthetic damage.Timely and accurate diagnosis are crucial for the treatment and management of patients.Yet,challenges persist in its diagnosis.This review explores the latest advancements in the diagnosis of LS,including high-frequency ultrasound,magnetic resonance imaging(MRI),optical coherence tomography(OCT),and molecular and genetic testing.These technologies have enhanced the precision and immediacy of diagnosis.High-frequency ultrasound allows the precise assessment of skin lesions,while MRI aids in evaluation of deep tissue involvement.OCT and der-moscopy reveal minor structural changes in the skin,and molecular and genetic testing offer new perspectives on understanding the disease mechanisms and individualized treatment.Despite limi-tations due to cost and availability of technology,these advancements hold significant potential in improving diagnostic protocols and providing personalized treatment plans.Future research should further explore the integration of these technologies with traditional methods and their application across different subtypes and stages of the disease.关键词
局限性硬皮病/高频超声/磁共振成像/光学相干断层扫描/分子和基因检测Key words
localized scleroderma/high-frequency ultrasound/magnetic resonance ima-ging/optical coherence tomography/molecular and genetic testing引用本文复制引用
曾松录,黄久佐,龙笑..局限性硬皮病诊断技术研究进展[J].皮肤性病诊疗学杂志,2024,31(5):334-339,6.基金项目
中央高水平医院临床科研基金(2022-PUMCH-A-210 （）
2022-PUMCH-C-025) （）
