皮肤性病诊疗学杂志2024，Vol.31Issue(5)：353-358,6.DOI:10.3969/j.issn.1674-8468.2024.05.010
佩索利单抗治疗泛发性脓疱型银屑病1例并文献复习
Treatment of generalized pustular psoriasis with Spesolimab:a case report and literature review
梁晓茜 1米泽曦 1许瑶函 1陈永锋2
作者信息
- 1. 南方医科大学,广东 广州 510515||南方医科大学皮肤病医院,广东 广州 510091
- 2. 南方医科大学皮肤病医院,广东 广州 510091
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of Spesolimab in the treatment of generalized pustular psoriasis(GPP).Methods A 30 years old female with GPP was intrave-nously given 900 mg of Spesolimab once.The safety and the changes in modified generalized pus-tular psoriasis area severity index(GPPASI)and generalized pustular psoriasis physician global assessment(GPPGA)were evaluated.Results After 1 week of the treatment,the GPPGA reached 2.After 2 months of the treatment,pustules almost completely subsided and both GPPASI and GPPGA reached 1.During the treatment,the patient developed anaphylactic adverse reac-tions,which were improved following the injection of betamethasone,antihistamine and symptom-atic therapy.Conclusion Spesolimab is an effective and safe agent for the treatment of general-ized pustular psoriasis.关键词
泛发性脓疱型银屑病/佩索利单抗/生物制剂/文献复习Key words
generalized pustular psoriasis/Spesolimab/biologic agent/literature review引用本文复制引用
梁晓茜,米泽曦,许瑶函,陈永锋..佩索利单抗治疗泛发性脓疱型银屑病1例并文献复习[J].皮肤性病诊疗学杂志,2024,31(5):353-358,6.
