青岛大学学报（医学版）2024，Vol.60Issue(2)：218-221,4.DOI:10.11712/jms.2096-5532.2024.60.067
中国中老年女性脂质积累产物和内脏脂肪指数与膝骨关节炎的关联性
Association of lipid accumulation products and visceral fat index with knee osteoarthritis in middle-aged and elderly Chinese women
摘要
Abstract
Objective To evaluate the association of lipid accumulation products(LAPs)and visceral adiposity index(VAI)with knee osteoarthritis(KOA)in middle-aged and elderly Chinese women.Methods The data were collected from the China Health and Retirement Longitudinal Study(CHARLS)database in 2011.The association of LAPs and VAI with the development of KOA was analyzed using the Logistic regression and receiver operating characteristic(ROC)curve.Results The prevalence of KOA was 34.01％(1 257/3 696)in Chinese women aged ≥45 years.Univariate Logistic regression analysis showed that in-creased LAPs(OR=1.013,95％CI=1.012-1.014)and VAL(OR=1.137,95％CI=1.117-1.158)were associated with the de-velopment of KOA.After adjustment for confounding factors,increased LAPs(OR=1.003,95％CI=1.002-1.004)and VAI(OR=1.048,95％CI=1.029-1.069)were still significantly associated with the development of KOA.The area under the ROC curve was 0.725(95％CI=0.709-0.741)for LAPs and 0.630(95％CI=0.613-0.647)for VAI.Conclusion Increased LAPs and VAI are risk factors for the development of KOA.LAPs has certain value in predicting the development of KOA in middle-aged and elderly women.关键词
膝骨关节炎/脂质沉积指数/腹内脂肪Key words
knee osteoarthritis/lipid accumulation product/intra-abdominal fat分类
医药卫生引用本文复制引用
张浩运,孙泽文,赵夏,于腾波..中国中老年女性脂质积累产物和内脏脂肪指数与膝骨关节炎的关联性[J].青岛大学学报（医学版）,2024,60(2):218-221,4.基金项目
2021年度山东省重点研发计划项目(31741063) （31741063）
