青岛大学学报（医学版）2024，Vol.60Issue(2)：233-238,6.DOI:10.11712/jms.2096-5532.2024.60.053
实时三维斑点追踪成像技术在维持性血液透析病人左心功能评价中的应用
Application of real-time three-dimensional speckle tracking imaging in evaluating left ventricular function in patients undergoing main-tenance hemodialysis
摘要
Abstract
Objective To investigate the clinical value of real-time three-dimensional speckle tracking imaging(RT3D-STI)in assessing myocardial function of uremia patients with preservation of left ventricular ejection fraction.Methods A total of 118 patients who attended our hospital and were diagnosed with uremia were enrolled in this study,and according to whether the pa-tient received maintenance hemodialysis,they were divided into hemodialysis group and non-hemodialysis group with 21 patients;the hemodialysis group was further divided into group A with 45 patients(duration of hemodialysis＜1 year),group B with 28 pa-tients(duration of hemodialysis ≥1 year and ≤3 years),and group C with 24 patients(duration of hemodialysis＞3 years and 5 years);30 healthy volunteers during the same period of time were enrolled as control group.RT3D-STI was used to measure the global longitudinal strain(GLS),global radial strain(GRS),and global circumferential strain(GCS)of the left ventricle and the time to peak longitudinal strain(TLS),time to peak radial strain(TRS),and time to peak circumferential strain(TCS)of myocar-dial exercise of the left ventricle,and the differences in parameters between groups were analyzed,as well as the correlation be-tween ultrasound and clinical parameters.Results Compared with the control group,the non-hemodialysis group and the hemo-dialysis group had significant reductions in GLS and GRS and significant increases in TLS and TRS(F=9.234-21.592,P＜0.05);compared withthe non-hemodialysis group,the hemodialysis group had a significant increase in GLS and a significant reduction in TLS(P＜0.05);compared with group A,groups B and C had a significant reduction in GLS and a significant increase in TLS(P＜0.05).In the patients with uremia,GLS and GRS were negatively correlated with left ventricular mass index and end-diastolic ve-locity(r=-0.609 to-0.446,P＜0.01)and were positively correlated with left ventricular ejection fraction(r=0.553,0.513,P＜0.01).Conclusion By measuring the global strains of the left ventricle and the time to peak strains of myocardial movement in uremia patients with preservation of left ventricular ejection fraction,RT3D-STI can track myocardial movement,accurately evaluate the changes in left ventricular myocardial movement,and assess the overall and local functions of the left ventricle,and therefore,it has an important clinical application value.关键词
尿毒症/肾透析/超声心动描记术,三维/成像,三维/心室功能,左Key words
uremia/renal dialysis/echocardiography,three-dimensional/imaging,three-dimensional/ventricular function,left分类
医药卫生引用本文复制引用
杨攀玉,宋晓霞,孙品,何香芹,王小凡,姜志荣..实时三维斑点追踪成像技术在维持性血液透析病人左心功能评价中的应用[J].青岛大学学报（医学版）,2024,60(2):233-238,6.基金项目
青岛市科技惠民重大项目(19-6-1-2-nsh) （19-6-1-2-nsh）
