青岛大学学报（医学版）2024，Vol.60Issue(2)：310-312,3.DOI:10.11712/jms.2096-5532.2024.60.042
肝源性糖尿病1例并文献复习
Hepatogenous diabetes:a case report and literature review
摘要
Abstract
Objective To investigate the pathogenesis,diagnosis,and treatment of hepatogenous diabetes.Methods A retrospective analysis was performed for the medical records of a case of hepatogenous diabetes,and a literature review was per-formed.Results The middle-aged male patient had elevated blood glucose for 8 years and poor blood glucose control for more than 2 months,with a history of hepatitis B cirrhosis for more than 20 years.He denied the family history of diabetes and had a family history of hepatitis B.Clinical manifestation and laboratory tests showedliver function damage,and the serum C-peptide re-lease test showed delayed peak secretion and a relatively low peak value.The patient did not use drugs causing glucose metabolism disorders,and secondary hyperglycemia caused by other causes was excluded.Therefore,the patient was diagnosed with hepatoge-nous diabetes and was given diabetic diet and the treatment regimen of anti-hepatitis B virus drugs,linagliptin,and insulin intensive treatment,which helped to achieve stable blood glucose control.Conclusion At present,there is no unified standard for the diagnosis of hepatogenous diabetes,and diagnosis should be made through a comprehensive analysis of medical history,clinical manifestations,and laboratory evidence.Hepatogenous diabetes is mainly caused by pancreatic βcell dysfunction and insulin resis-tance,and an individualized comprehensive treatment regimen based on the treatment of primary liver diseases should be adopted,with considerations to diet,exercise,and hypoglycemic drugs.关键词
糖尿病/乙型肝炎/肝硬化/病例报告Key words
diabetes mellitus/hepatitis B/liver cirrhosis/case reports分类
医药卫生引用本文复制引用
宋丽媛,荆菁,马小莉,于民民,赵蕙琛,刘元涛..肝源性糖尿病1例并文献复习[J].青岛大学学报（医学版）,2024,60(2):310-312,3.基金项目
青岛市创新领军人才项目(16-8-3-24-zhc) （16-8-3-24-zhc）
