肿瘤预防与治疗2024，Vol.37Issue(5)：421-428,8.DOI:10.3969/j.issn.1674-0904.2024.05.008
术前预康复在晚期卵巢癌患者中的临床应用效果
Clinical Effect of Preoperative Prehabilitation in Patients with Advanced Ovarian Cancer
摘要
Abstract
Objective:To analyze and discuss the clinical effects and feasibility of preoperative rehabilitation model ap-plied to patients with advanced ovarian cancer.Methods:A retrospective analysis was conducted on the data of 80 patients with advanced ovarian cancer who underwent neoadjuvant chemotherapy combined with interval debulking surgery in the de-partment of gynecology in the First Affiliated Hospital of Army Medical University from January 2022 to December 2023.Ac-cording to different preoperative rehabilitation decisions,patients were assigned to a control group of 40 cases,implementing routine nursing measures;and an experiment group of 40 cases,implementing preoperative prehabilitation plan on the basis of routine nursing.The differences in 6-mi-nute walk distance(6MWD),serum albumin level and hemo-globin level 1day before neoadjuvant chemotherapy,1day before surgery and 30days after surgery as well as the incidence rates of postoperative complications and postoperative recovery indicators between the two groups were compared.Results:1day before surgery,the experiment group had a greater 6MWD than the control group[(434.00±17.79)m vs(421.08± 19.70)m,P=0.003)];the serum albumin level and hemoglobin level in the experiment group were higher than those in the control group[(42.68±2.09)g/L vs(40.33±5.31)g/L,P=0.011;(114.33±8.44)g/L vs(108.20±15.77)g/L,P=0.034].At 30 days after surgery,the experimental group's 6MWD was greater than that of the control group[(440.26±10.56)m vs(426.50±17.65)m,P＜0.001);the serum albumin level and hemoglobin levels were higher than those in the control group[(42.06±2.89)g/L vs(40.50±3.60)g/L,P=0.035;(113.53±6.50)g/L vs(104.10±11.90)g/L,P＜0.001].Differences in the incidence rate of 30-day postoperative complications[25.00％(10/40)vs 37.50％(15/40),P=0.045],Huaxi Emotional-Distress Index,total length of days,postoperative length of days and total hospital costs were all statistically significant between the experiment group and the control group(P＜0.05).Conclusion:Preoperative prehabilitation is helpful in improving exercise capacity,nutritional status,reducing the incidence of postoperative complications,shortening length of stay,and promoting enhanced recovery after surgery for patients with ad-vanced ovarian cancer.关键词
晚期卵巢癌/新辅助化疗/术前预康复/加速康复/术后并发症Key words
Advanced ovarian cancer/Neoadjuvant chemotherapy/Preoperative prehabilitation/ERAS/Postoperative complications分类
医药卫生引用本文复制引用
荣欣,吴治敏,王艳,陈彦丽,李玲,邓黎..术前预康复在晚期卵巢癌患者中的临床应用效果[J].肿瘤预防与治疗,2024,37(5):421-428,8.基金项目
This study was supported by grants from Chongqing Science and Technology Bureau and Health Commis-sion of Chongqing(No.2024MSXM018). 重庆市科卫联合医学科研项目(编号:2024MSXM018) （No.2024MSXM018）
