四川中医2024，Vol.42Issue(5)：173-177,5.
雷火灸联合中药热奄包对食管癌放化疗患者增效减毒效果观察
Observation on the effect of thunder fire moxibustion combined with Chinese medicine Remai Bao on enhancing and reducing toxicity of esophageal cancer patients with radiotherapy and chemotherapy
摘要
Abstract
Objective:To investigate the effect of thunder fire moxibustion combined with Chinese medicine Remai Bao on enhancing the efficacy and reducing the toxicity of esophageal cancer patients with radiotherapy and chemotherapy.Methods:86cases of patients with esophageal cancer were admitted to our hospital from April 2021to April 2023were selected,they were di-vided into two groups by numerical random table method,43cases in the control group were received conventional chemoradiother-apy,and 43cases in the observation group were received the treatment of thunder fire moxibustion combined with traditional Chi-nese medicine hot ambao on the basis of conventional chemoradiotherapy.The immune function,efficacy of chemoradiotherapy,occurrence of adverse reactions,liver and kidney function indexes,symptoms related to food intake and quality of life were com-pared between the two groups.Results:The levels of CD4+T and CD8+T in observation group were higher than those in control group at the end of treatment(P＜0.05).In the observation group,the total effective rate was 93.02％,which was higher than 4.42％in control group(P＜0.05).In the observation group,the incidence of adverse reactions was 11.63％,which was lower than 34.88％in the control group(P＜0.05),and at the end of treatment,the levels of aspartate transferase(AST),alanine aminotransferase(ALT),cystatin C(CysC)and creatinine(CREA)in observation group were lower than those in control group(P＜0.05).In the observation group,the score of Anderson symptom assessment scale(MDASI-GI)score of at the end of treatment was lower than that of the control group(P＜0.05).In the observation group,the Chinese version of quality of life scale for cancer patients(EORTCQLQ-C30)score at the end of treatment was better than that in the control group(P＜0.05).Conclusion:The application of thunder fire moxibustion combined with Chinese medicine Remei Bao in patients with esophageal cancer can improve their immune function,achieve a good effect of enhancing efficiency and reducing toxicity,reduce adverse re-actions,reduce the degree of liver and kidney function damage,and help to further improve patients'ingestion related symptoms and improve their quality of life.关键词
雷火灸/中药热奄包/食管癌/放化疗/增效减毒/生活质量Key words
Lightning moxibustion/Traditional Chinese medicine Hot Smoothing Bag/Esophageal cancer/Chemoradiother-apy/Increase efficiency and decrease toxicity/Quality of life分类
医药卫生引用本文复制引用
时代,李伟,刘海燕,张婧,李守山..雷火灸联合中药热奄包对食管癌放化疗患者增效减毒效果观察[J].四川中医,2024,42(5):173-177,5.基金项目
国家中医药管理局"胃癌毒邪论治"重点研究室开放课题项目(编号:202137). （编号:202137）
