摘要
Abstract
Objective To explore the efficacy of intranasal acupuncture at Biqiu acupoint and Neiyingxiang acupoint combined with traditional Chinese medicine application in the treatment of allergic rhinitis and its influence on nasal secretion eosinophil percentage(EOS％),serum total immunoglobulin E(IgE),interleukin-4(IL-4)and substance P(SP)levels.Methods 60patients with allergic rhinitis who received treatment at the outpatient department of our hospital from January 2021to May 2023were selected and divided into a control group and an observation group according to the treatment method.Each group had 30patients.The control group was given a modern treatment plan(warm physiological saline nasal cavity,oral loratadine tablets,and nasal spray of mometasone furoate aerosol),and the observation group received nasal acupuncture combined with acupoint ap-plication based on the above treatment plan to evaluate the efficacy of traditional Chinese medicine symptoms in both groups,Compare the changes in traditional Chinese medicine nasal symptom scores,EOS％of nasal secretions,eosinophil activated che-mokine(eotaxin)levels,and serum total IgE,IL-4,and SP levels between the two groups before and after 4weeks of treatment.Results The efficacy of TCM syndrome in the observation group after 4weeks of treatment was significantly better than that in con-trol group(P＜0.05),and the total effective rate was significantly higher(P＜0.05).After 4weeks of treatment,the scores of four main TCM nasal symptoms such as frequent sneezing,clear water-like nasal discharge,nasal itching and nasal congestion were obviously declined compared with those before treatment(P＜0.05),and the nasal secretion EOS％,eotaxin content and se-rum total IgE,IL-4and SP levels were significantly reduced compared to before treatment(P＜0.05),and the above indicators were significantly lower in observation group than those in control group(P＜0.05).Conclusion Intranasal acupuncture at Biqiu acupoint and Neiyingxiang acupoint combined with traditional Chinese medicine application has a significant efficacy of TCM syn-dromes in treating allergic rhinitis,and it can relieve the nasal symptoms,inhibit the nasal secretion EOS％and eotaxin content and serum total IgE,IL-4and SP levels.关键词
鼻内针刺鼻丘穴/内迎香穴/中药贴敷/过敏性鼻炎/鼻腔分泌物EOS％/血清总IgE/血清IL-4/血清SPKey words
Intranasal acupuncture at Biqiu acupoint/Neiyingxiang acupoint/Traditional Chinese medicine paste/rhinal-lergosis/Nasal secretion EOS％/Serum total IgE/Serum IL-4/Serum SP分类
医药卫生
