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姜黄素在心血管疾病中的作用与新型给药策略研究进展

韩拓 闫保娥 张静若 李雯 张岩

药学研究2024,Vol.43Issue(5):461-465,494,6.
药学研究2024,Vol.43Issue(5):461-465,494,6.DOI:10.13506/j.cnki.jpr.2024.05.009

姜黄素在心血管疾病中的作用与新型给药策略研究进展

Research progress on the effects and novel drug delivery strategies of curcumin in cardiovascular diseases

韩拓 1闫保娥 2张静若 1李雯 1张岩1

作者信息

  • 1. 西安交通大学第二附属医院,陕西 西安 710004
  • 2. 延安大学附属医院心脑血管病医院,陕西 延安 716000
  • 折叠

摘要

Abstract

Cardiovascular disease(CVD)is the first killer of human life and health,causing heavy health and economic burden.Curcumin,a polyphenol compound,is the main active compound in traditional Chinese medicine turmeric.In recent years,studies have reported that curcumin has anti-inflammatory,antioxidant,hypolipidemic,antithrombotic and other beneficial effects,and is expected to become a potential drug for clinical treatment of cardiovascular diseases.Here,we give a summary of the latest research progress on the mechanism and novel drug delivery strategies of curcumin in cardiovascular diseases in past three years,thus to provide theoretical basis for the application of curcumin in the prevention and treatment of cardiovascular diseases.

关键词

姜黄素/动脉粥样硬化/心力衰竭/糖尿病心肌病/药物递送

Key words

Curcumin/Atherosclerosis/Heart failure/Diabetic cardiomyopathy/Drug delivery

分类

中医学

引用本文复制引用

韩拓,闫保娥,张静若,李雯,张岩..姜黄素在心血管疾病中的作用与新型给药策略研究进展[J].药学研究,2024,43(5):461-465,494,6.

基金项目

国家自然科学基金青年项目(No.82100359) (No.82100359)

陕西省自然科学青年基金(No.2020JQ-552) (No.2020JQ-552)

药学研究

OACSTPCD

2095-5375

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