山西大学学报（自然科学版）2024，Vol.47Issue(3)：624-636,13.DOI:10.13451/j.sxu.ns.2023128
氯掺杂增强四氧化三钴类过氧化物酶活性机制研究及应用
Mechanism of Chloride Doping to Enhance Peroxidase Activity of Co3O4 Nanocrystals and Its Application
摘要
Abstract
Nanozymes as nanomaterials with enzyme-like activity are a new frontier of chemical research.However,the low catalytic activity of nanozymes limits their application.Therefore,designing nanozymes with high catalytic activity has become a hot spot in this field.Herein,Cl― doped Co3O4 nanocrystals(NCs)were successfully prepared by the solid-phase grinding method.After doping,their peroxidase-like(POD-like)initial reaction rate was increased about 1.3 times.Cl― doping enhanced the H2O2 decomposition to superoxide anion radical(O2·―),making the production of hydroxyl radical(·OH)possible.As the·OH is more oxidizing than O2·―,the POD-like activity of Cl― doped Co3O4 NCs is significantly enhanced.The electron paramagnetic resonance(EPR)and X-ray photoelectron spectroscopy(XPS)investigations implied that the increase of oxygen vacancy and the change of electronic structure of Co3O4 NCs after doping were the primary reasons for the enhanced POD-like activity.At the same time,the solid-phase grinding-assisted halogen doping method was successfully applied to other metal oxide NCs,and the beneficial effect of enhancing their POD-like activities was also obtained.In this study,we developed a simple modification method for metal oxide NCs based on halogen doping.This method may provide a new way for the rational design of nanozyme with highly efficient POD-like activity.关键词
固相研磨法/Cl―掺杂/Co3O4纳米晶/类过氧化物酶Key words
solid-phase grinding method/Cl― doping/Co3O4 nanocrystals/peroxidase-like分类
数理科学引用本文复制引用
任亚丽,梁书丰,张云慧,代燕..氯掺杂增强四氧化三钴类过氧化物酶活性机制研究及应用[J].山西大学学报（自然科学版）,2024,47(3):624-636,13.基金项目
山西省自然科学基金(202103021224014) （202103021224014）
