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人参皂苷CK美容护肤作用及机制研究进展

叶萍 张慧娥 初孟瑶 侯剑峰 周蕖 魏琨 陈长宝 李光 王恩鹏

特产研究2024,Vol.46Issue(3):161-167,7.
特产研究2024,Vol.46Issue(3):161-167,7.DOI:10.16720/j.cnki.tcyj.2023.030

人参皂苷CK美容护肤作用及机制研究进展

Research Advances on Beauty and Skin Care Effect and Mechanism of Ginsenoside CK

叶萍 1张慧娥 1初孟瑶 1侯剑峰 2周蕖 3魏琨 4陈长宝 1李光 4王恩鹏1

作者信息

  • 1. 长春中医药大学,吉林省人参科学研究院,吉林 长春 130117
  • 2. 士齐生物研发中心(苏州工业园区)有限公司,江苏 苏州 215125
  • 3. 吉林紫鑫药业股份有限公司,吉林 长春 135300
  • 4. 长春中医药大学附属第一医院,吉林 长春 130117
  • 折叠

摘要

Abstract

Ginseng(Panax ginseng C.A.Mey.)has been widely used in China for thousands of years because of its superior medicinal and health care value,especially in beauty and skin care.At present,it has become one of the most important anti-aging,whitening and skin-re-juvenating ingredients in cosmetic raw materials in China and even in the world,and has been widely used in some international cosmetic brands in recent years.To explore the application of 20(S)protopanaxadiol-20 murine O-β-D-glucopyranoside(Compound K,CK)in gin-seng in recent years,the function and mechanism of CK in cosmetology and skin care in recent years were reviewed.CK has attracted much attention because it is a deglycemic metabolite derived from diol ginsenosides,which has higher bioavailability and solubility than its parent ginsenosides,and is easier to be absorbed by human body.It is found that CK has many functions of beauty and skin care,such as light pro-tection,anti-aging,moisturizing,anti-inflammation and so on.At present the research mainly focuses on the application mechanism of CK in ant-cancer,however,there are relatively few researches on skin beauty and care.This study summarizes the funtion of CK in skin care,and focuses on the molecular mechanism of CK skin care.This paper intends to provide a reference basis for the further research and devel-opment of CK in the field of beauty and skin care in the future.

关键词

人参皂苷CK/光保护/抗衰老/护肤机制/研究进展

Key words

ginsenoside CK/light protection/anti-aging/skin care mechanism/research progress

分类

医药卫生

引用本文复制引用

叶萍,张慧娥,初孟瑶,侯剑峰,周蕖,魏琨,陈长宝,李光,王恩鹏..人参皂苷CK美容护肤作用及机制研究进展[J].特产研究,2024,46(3):161-167,7.

基金项目

吉林省科技发展计划项目(20210401108YY、20200404042YY) (20210401108YY、20200404042YY)

长春市科技局重点研发计划项目(21ZGY10) (21ZGY10)

珈伊生化研发中心(苏州工业园区)有限公司项目(20191120) (苏州工业园区)

特产研究

OACSTPCD

1001-4721

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