同济大学学报（自然科学版）2024，Vol.52Issue(5)：788-795,8.DOI:10.11908/j.issn.0253-374x.22339
饮水系统中抗生素抗性基因赋存特征及健康风险评估
Occurrence and Health Risk Assessment of Antibiotic Resistance Genes in Drinking Water Systems
摘要
Abstract
Antibiotic resistance genes(ARGs)are widely distributed in water and soil as a new type of pollutants.Microorganisms which pose a potential threat to human health obtain antibiotic resistance through the proliferation of ARGs.In order to study the possible health risks of a large number of ARGs in urban drinking water systems at this stage,this paper first combines the data reported in the domestic and international literature,introduces the current situation of ARGs contamination in urban drinking water systems,describes their storage characteristics,and finds that the number of ARGs in urban drinking water systems at home and abroad is not to be underestimated,and the number of the highest number of ARGs can be up to 1.38×105 copies·ml-1.Then,it summarizes the influences of commonly used processes in urban drinking water systems on ARGs accumulation and propagation.It is found that commonly used water treatment processes in urban areas have poor inactivation effects on ARGs,and even tend to promote their enrichment and propagation.Among different environmental factors,microbial community structure is the main driving force influencing ARGs,followed by heavy metals.Finally,it proposes the possible health risks of ARGs to human beings and the limitations of the existing health risk assessment methods,and prospects the future research on ARGs.关键词
抗生素抗性基因(ARGs)/饮水系统/赋存特征/影响因素/健康风险Key words
antibiotic resistance genes(ARGs)/drinking water system/occurrence characteristics/influencing factor/health risk分类
资源环境引用本文复制引用
代朝猛,万罗超,游学极,赖小莹,刘曙光,张亚雷..饮水系统中抗生素抗性基因赋存特征及健康风险评估[J].同济大学学报（自然科学版）,2024,52(5):788-795,8.基金项目
国家重点研发计划(2019YFE0114900) （2019YFE0114900）
国家自然科学基金(42077175) （42077175）
