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高迁移率族蛋白B1在临床相关疾病中的作用研究进展

曾雨竹 吴一凡 孟林红 伍行 丁文文 屈小芹

现代医药卫生2024,Vol.40Issue(10):1759-1762,1767,5.
现代医药卫生2024,Vol.40Issue(10):1759-1762,1767,5.DOI:10.3969/j.issn.1009-5519.2024.10.029

高迁移率族蛋白B1在临床相关疾病中的作用研究进展

Research progress on the role of high mobility group box-1 protein in clinically relevant diseases

曾雨竹 1吴一凡 1孟林红 1伍行 1丁文文 2屈小芹2

作者信息

  • 1. 荆楚理工学院 医学部,湖北 荆门 448000
  • 2. 荆楚理工学院 基础医学教研室,湖北 荆门 448000
  • 折叠

摘要

Abstract

High mobility group box-1 protein(HMGB1)is a nuclear protein released by macrophages with late proinflammatory effect.In recent years,as a new type of inflammatory factor,HMGB1 has been widely studied by scholars at home and abroad.It has been found that this protein can act as an inflammatory mediator in many diseases,and then play a cytokine activity and participate in body damage.This article dis-cussed the damage of HMGB1 in cardiovascular system,kidney,liver,pancreas and other related diseases and its possible mechanism,in order to provide a basis for clinical diagnosis and research of relevant diseases.

关键词

高迁移率族蛋白B1/高血压/病毒性肝炎/急性胰腺炎/综述

Key words

High mobility group box-1 protein/Hypertension/Viral hepatitis/Acute pancreatitis/Review

分类

医药卫生

引用本文复制引用

曾雨竹,吴一凡,孟林红,伍行,丁文文,屈小芹..高迁移率族蛋白B1在临床相关疾病中的作用研究进展[J].现代医药卫生,2024,40(10):1759-1762,1767,5.

基金项目

湖北省大学生创新创业训练计划项目(S202211336039) (S202211336039)

湖北省教育厅科学研究计划资助项目(D20224301) (D20224301)

荆楚理工学院校级科研项目(ZD202001). (ZD202001)

现代医药卫生

1009-5519

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