畜牧兽医学报2024，Vol.55Issue(5)：1819-1826,8.DOI:10.11843/j.issn.0366-6964.2024.05.001
产单核细胞李氏杆菌噬菌体的应用研究进展
Research Progress of Applied Research on Listeria monocytogenes Phage
摘要
Abstract
Listeria monocytogenes being a common foodborne pathogen.Food contaminated with this bacterial can cause listeriosis,with clinical manifestations of sepsis and meningitis,and mortality be up to 30％.Listeria monocytogenes can survive under extreme condition such as high salinity,high acidity,and low temperature,so posing a significant threat to the human and animal health.At present,the main method of preventing and treating this disease is the use of antibiotics.However,the multiple drug resistance making the prevention and treatment of listeriosis extraordinarily difficult.The development of phage and related biological agents provides feasible solutions to solve the above problem.This article reviews the applications of Listeria phages in food preservation,biological detection,genetic engineering,and the interaction between phages and hosts,aiming to provide a theoretical basis for Listeria phages in food pollution prevention and control.关键词
李氏杆菌/噬菌体/食品污染/生物检测Key words
Listeria monocytogenes/phage/food contamination/biological detection分类
农业科技引用本文复制引用
崇倩,赵学慧,曹青,薛惠文,苟惠天..产单核细胞李氏杆菌噬菌体的应用研究进展[J].畜牧兽医学报,2024,55(5):1819-1826,8.基金项目
国家自然科学基金(32060822 （）
31960726 （）
31560700) （）
国家重点研发计划(2019YFC1605705) （2019YFC1605705）
