畜牧兽医学报2024，Vol.55Issue(5)：1893-1903,11.DOI:10.11843/j.issn.0366-6964.2024.05.008
反刍动物瘤胃微生物LuxS/AI-2群体感应研究进展
Research Progress on LuxS/AI-2 Quorum Sensing of Rumen Microbe in Ruminants
摘要
Abstract
Quorum sensing(QS)is a communication mechanism utilized by bacteria to facilitate intra-species or inter-species communication through the signaling molecules.Through this communication mechanism,microorganisms can collectively conduct physiological functions or regulate behaviors that cannot be achieved by microbial individual.These functions include biofilm formation,toxin secretion,bioluminescence,and other adaptive responses to enhance the adaptability of microorganisms against external stress environment.Recently,multi-omics studies have revealed that LuxS/AI-2 QS,mediated by the autoinducer-2(AI-2)signaling molecule and regulated by the LuxS protein,serves as the primary communication mechanism among rumen microbe,influencing their efficiency in feed utilization.This review provides a summary of the LuxS/AI-2 QS in rumen microbe,focusing on the chemical structure of AI-2 and its transduction pathways.The roles of LuxS/AI-2 QS in rumen microbial colonization and feed digestion in ruminants were reviewed,as well as the potential roles of LuxS/AI-2 QS in feed digestion and stress regulation.This review may provide a theoretical reference for production strategy by regulating the digestive metabolism and homeostasis of rumen microbe through LuxS/AI-2 QS.关键词
LuxS/AI-2群体感应/生物膜/瘤胃微生物/群落稳定性/饲料消化Key words
LuxS/AI-2 quorum sensing/biofilm/rumen microbe/community stability/feed digestion分类
生物科学引用本文复制引用
龙唐晖,周江汇,詹彦波,张健,赵向辉,李艳娇,欧阳克蕙,邱清华..反刍动物瘤胃微生物LuxS/AI-2群体感应研究进展[J].畜牧兽医学报,2024,55(5):1893-1903,11.基金项目
国家自然科学基金项目(32260861 （）
32160807) （）
江西省自然科学基金资助项目(20232BAB215051) （20232BAB215051）
江西省主要学科学术和技术带头人培养计划"领军人才"项目(20213BCJL22043) （20213BCJL22043）
江西农业大学年轻科研创新团队项目(JXAUCXTD008) （JXAUCXTD008）
