基于SNP分子标记的湖羊群体遗传结构分析OA北大核心CSTPCD

Modern bioinformatics technology was used in this study to evaluate the genetic structure and to construct detailed pedigree re-cords of Hu rams.Forty breeding rams were used and SNP site detection was performed on them.Then,genetic structure analysis,principal component analysis,and evolutionary tree construction were conducted in the Hu sheep.The results showed that a total of 952 214 SNPs were detected on 40 rams.The average nucleotide diversity of these sites was between 0.212 9 and 0.242 5.Their average observed heterozygosity(Ho)was greater than the average expected heterozygosity(He).The degree of their genetic differentiation was between 0.370 2 and 0.452 4.The genetic distance of their IBS was between 0.173 9 and 0.228 0,with an average of 0.220 9.The result of the principal compo-nent analysis was consistent with that of the phylogenetic tree.Taken together,the 40 rams could be divided into 14 families.The kinship be-tween most of the individuals was distant.The present results indicated that Hu rams possessed high genetic diversity and selection potential,which contributed to a more complete pedigree record of Hu rams and provided scientific support for breeding and mating of Hu Sheep on farms.