畜牧与兽医2024，Vol.56Issue(6)：1-8,8.
基于SNP分子标记的湖羊群体遗传结构分析
Analysis of the genetic structure of Hu sheep population based on SNP molecular markers
摘要
Abstract
Modern bioinformatics technology was used in this study to evaluate the genetic structure and to construct detailed pedigree re-cords of Hu rams.Forty breeding rams were used and SNP site detection was performed on them.Then,genetic structure analysis,principal component analysis,and evolutionary tree construction were conducted in the Hu sheep.The results showed that a total of 952 214 SNPs were detected on 40 rams.The average nucleotide diversity of these sites was between 0.212 9 and 0.242 5.Their average observed heterozygosity(Ho)was greater than the average expected heterozygosity(He).The degree of their genetic differentiation was between 0.370 2 and 0.452 4.The genetic distance of their IBS was between 0.173 9 and 0.228 0,with an average of 0.220 9.The result of the principal compo-nent analysis was consistent with that of the phylogenetic tree.Taken together,the 40 rams could be divided into 14 families.The kinship be-tween most of the individuals was distant.The present results indicated that Hu rams possessed high genetic diversity and selection potential,which contributed to a more complete pedigree record of Hu rams and provided scientific support for breeding and mating of Hu Sheep on farms.关键词
湖羊/单核苷酸多态性/遗传多样性/遗传结构/亲缘关系Key words
Hu sheep/SNP/genetic diversity/genetic structure/kinship分类
农业科技引用本文复制引用
马敏彪,武利恒,丁琳,金慧佳,赵丽莉,曹丁壬,王争光..基于SNP分子标记的湖羊群体遗传结构分析[J].畜牧与兽医,2024,56(6):1-8,8.基金项目
衢州市科技局项目(2023T019) （2023T019）
浙江省农业重大技术协同推广计划项目(2023ZDXT16) （2023ZDXT16）
浙江省科技厅项目(2023C04004) （2023C04004）
浙江省畜禽新品种选育重大科技专项(2021C02068-6) （2021C02068-6）
国家自然科学基金项目(32172724) （32172724）
