刑事技术2024，Vol.49Issue(3)：262-267,6.DOI:10.16467/j.1008-3650.2023.0055
毛发中甲基苯丙胺检验的样品前处理方法研究
Study on Sample Pretreatment Methods for Determination of Methamphetamine in Hair Samples
摘要
Abstract
By analyzing and studying the hair samples that contain methamphetamine,the paper aims to explore the optimal pretreatment conditions when determining methamphetamine in hair using liquid chromatography-tandem mass spectrometry(LC-MS/MS).Different cleaning,grinding,and extraction conditions were compared to optimize the pretreatment method.Retention time,characteristic ion pairs and their relative abundance were used for qualitative determination.The peak area of characteristic ion pairs was used for quantification.The results showed that the concentration of methamphetamine in hair was the highest when extracted by methanol grinding.In this paper,the impact of pretreatment methods on the results of methamphetamine analysis in hair by LC-MS/MS was systematically studied and analyzed,and an optimal pretreatment condition was explored for the qualitative and quantitative detection of methamphetamine in hair samples.关键词
法医毒物学/毛发/甲基苯丙胺/样品前处理Key words
forensic toxicology/hair samples/methamphetamine/sample pretreatment分类
社会科学引用本文复制引用
于交远,包少魁,王爱华,董林沛,王瑞花,邹波,李佳宜,吴小军..毛发中甲基苯丙胺检验的样品前处理方法研究[J].刑事技术,2024,49(3):262-267,6.基金项目
公安部技术研究计划项目(2020JSYJC11) （2020JSYJC11）
中央级公益性科研院所基本科研业务费专项资金项目(2021JB007) （2021JB007）
