新医学2024，Vol.55Issue(5)：328-334,7.DOI:10.3969/j.issn.0253-9802.2024.05.002
治疗前格拉斯哥评分及血液炎性指标与鼻咽癌患者预后相关性研究
Study on the correlation between pre-treatment Glasgow score and blood inflammatory markers and prognosis of nasopharyngeal carcinoma patients
摘要
Abstract
Objective To investigate the correlation between Glasgow score and blood inflammatory markers before treatment with the efficacy of nasopharyngeal carcinoma.Methods Cases from the two clinical centers were divided into training set and validation set,and the clinical characteristics of the two groups were compared to be balanced.To search the independent prognostic risk factors of nasopharyngeal carcinoma and then the prognostic index of each patient was calculated,and the patients were divided into high-risk,intermediate-risk and low-risk groups.Further validation in the validation set.Results Cox multivariate analysis of the training set showed that age>50,T3-T4,N2-N3,GPS score of 1-2,NLR>2.5,and LMR≤2.35 before treatment were poor prognostic factors affecting the 5-year disease-specific survival rate of patients with nasopharyngeal carcinoma.Conclusion The combination of GPS,NLR,LMR and age,TNM staging may provide a new way for the prognosis evaluation of patients with nasopharyngeal carcinoma before treatment.关键词
鼻咽癌/中性粒细胞与淋巴细胞比值/格拉斯哥预后评分/血小板与淋巴细胞比值/淋巴细胞与单核细胞比值Key words
Nasopharyngeal carcinoma/Glasgow prognostic score/Neutrophil lymphocyte ratio/Platelet lymphocyte ratio/Lymphocyte mononuclear ratio引用本文复制引用
李晓惠,许啸,范元平,文娟,陈静茹,夏云飞..治疗前格拉斯哥评分及血液炎性指标与鼻咽癌患者预后相关性研究[J].新医学,2024,55(5):328-334,7.基金项目
国家高技术研究发展计划(863计划)(2006AA0224B4) （863计划）
广东省医学科学技术研究基金项目(A2018552 （）
B2022288) （）
