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用于皮肤温度振荡分析和微血管功能评估的系统设计及应用

唐元梁 谭仲威 刘奇 李桂香

中国医疗设备2024,Vol.39Issue(6):1-7,29,8.
中国医疗设备2024,Vol.39Issue(6):1-7,29,8.DOI:10.3969/j.issn.1674-1633.2024.06.001

用于皮肤温度振荡分析和微血管功能评估的系统设计及应用

Design and Application of System for Skin Temperature Oscillation Analysis and Microvascular Function Evaluation

唐元梁 1谭仲威 1刘奇 1李桂香1

作者信息

  • 1. 广东省科学院生物与医学工程研究所,广东 广州 510000||广东省医用电子仪器及高分子材料制品重点实验室,广东 广州 510000||广东省中医药智慧诊疗工程技术研究中心,广东 广州 510000
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摘要

Abstract

Objective To design and achieve a skin temperature oscillation analysis system for the evaluation of microvascular regulatory functions.Methods The local thermal stimulation was used by skin temperature oscillation analysis system,composed of portable instruments and analysis software to induce human skin to produce congestion reaction.The skin temperature change signals before and after congestion reaction were collected in real time,and the amplitude of skin temperature oscillation based on continuous wavelet transform was analyzed,and the evaluations of skin microvascular endothelial,nerve and myogenic regulatory functions were realized finally.Results Experimental studies using developed system found that thermal stimulation at 40-41℃significantly enhanced the intensity of skin temperature oscillations.The fluctuation amplitude of skin temperature in the endothelium(0.0095-0.0200 Hz),neurogenic(0.02-0.05 Hz)and myogenic(0.05-0.14 Hz)frequency bands were 2.20,4.28 and 2.77 times of those without thermal stimulation,respectively.Conclusion This study verifies the enhanced amplitude of skin temperature oscillations under thermal stimulation conditions,which can be used to quantify the functions of skin microvascular movement regulation.The skin temperature oscillation analysis system designed and developed in this paper provides an effective tool for the evaluation of microvascular regulatory functions.

关键词

小波分析/血管运动/测温/反应性充血

Key words

wavelet analysis/vasomotion/temperature measurement/reactive hyperaemia

分类

医药卫生

引用本文复制引用

唐元梁,谭仲威,刘奇,李桂香..用于皮肤温度振荡分析和微血管功能评估的系统设计及应用[J].中国医疗设备,2024,39(6):1-7,29,8.

基金项目

广东省自然科学基金青年提升项目(2024A1515030052) (2024A1515030052)

广东省科学院"千名博士(后)计划"引进专项(2020GDASYL-20200103037 (后)

2021GDASYL-20210103028) ()

广东省科学院发展专项资金项目(2022GDASZH-2022010110 ()

2023GDASZH-2023010102 ()

2022GDASZH-2022020402-01) ()

广州市科技计划项目基础与应用基础研究专题(2023A04J1846). (2023A04J1846)

中国医疗设备

OACSTPCD

1674-1633

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