医学信息2024,Vol.37Issue(11):175-179,188,6.DOI:10.3969/j.issn.1006-1959.2024.11.037
艾滋病合并丙型肝炎感染的转录组学研究
Transcriptomic Study of AIDS Complicated with Hepatitis C Infection
摘要
Abstract
AIDS and hepatitis C are two common infectious diseases with the same route of transmission,which can be infected through blood,sexual contact,mother-to-child vertical transmission and so on.AIDS combined with hepatitis C infection can aggravate liver damage,lead to the increase of the possibility of developing into chronic infection,and seriously endanger human health and life safety.At present,the mechanism of hepatitis C and co-infection with AIDS in the human body is not clear.Therefore,this paper summarizes the related contents of peripheral blood transcriptomics in patients with AIDS and co-infection with hepatitis C.By exploring the related immune pathways and gene expression differences,it provides new ideas for the interaction between AIDS,hepatitis C and host,pathogenic mechanism and new drug development,and provides important theoretical significance and clinical application value for the diagnosis,treatment and prevention of AIDS and hepatitis C.关键词
艾滋病/丙型肝炎/转录组学Key words
AIDS/Hepatitis C/Transcriptomics分类
医药卫生引用本文复制引用
亢丽娟,刘俊仪,王佳丽..艾滋病合并丙型肝炎感染的转录组学研究[J].医学信息,2024,37(11):175-179,188,6.基金项目
1.国家自然科学基金项目(编号:81960605) (编号:81960605)
2.云南省教育厅科学研究基金项目(编号:2019J1305) (编号:2019J1305)
3.云南省科技厅科技计划项目(编号:202101AY070001-223、202102AA310005-033) (编号:202101AY070001-223、202102AA310005-033)
4.昆明医科大学科技创新团队建设项目(编号:CXTD202111) (编号:CXTD202111)