摘要
Abstract
Objective To explore the application of narrow-band imaging-magnifying endoscopy(NBI-ME)in screening for early cancer of upper digestive tract and precancerous lesions.Methods A total of 68 patients suspected of early cancer of upper digestive tract and precancerous lesions treated at Beihai Hospital in Xuchang from July 2021 to July 2023 were selected.All patients underwent routine endoscopic and NBI-ME examinations,and pathological results were used as the gold standard to analyze diagnostic efficacy.Results After pathological examination,68 suspected patients with early cancer of upper digestive tract and precancerous lesions were found to have 8 cases of benign lesions,22 cases of precancerous lesions,18 cases of early cancer of upper digestive tract,and 20 cases of advanced cancer.The diagnostic accuracy and specificity of NBI-ME were 97.06%and 100.00%,which were higher than those of conventional endoscopy(80.88%and 62.50%),and the difference was statistically significant(P＜0.05);The sensitivity of NBI-ME(96.67%)was higher than that of conventional endoscopy(83.33%),and the difference was not statistically significant(P＞0.05);There are differences in the characteristic manifestations of benign lesions and tumor lesions under NBI-ME microscopy,including the boundary line,mucosal microvasculature,mucosal surface glandular ducts,increased glandular duct density,and increased mucosal microvascular density,with statistical significance(P＜0.05);The clarity of lesion contour,gastrointestinal mucosa,and microvascular morphology in NBI-ME examination was higher than that in conventional endoscopy,and the difference was statistically significant(P＜0.05).Conclusion NBI-ME has high diagnostic efficacy and specificity in screening early cancer of upper digestive tract and precancerous lesions,and can provide clear images for clinical diagnosis,providing guidance for clinical diagnosis and treatment.关键词
窄带成像-放大内镜/上消化道癌/癌前病变/筛查Key words
narrowband imaging-magnifying endoscopy/early cancer of upper digestive tract/precancerous lesions/screening分类
医药卫生
