中国当代儿科杂志2024,Vol.26Issue(5):450-455,6.DOI:10.7499/j.issn.1008-8830.2311094
深圳市新生儿脑卒中多中心现况调查
A multicenter study of neonatal stroke in Shenzhen,China
摘要
Abstract
Objective To investigate the incidence rate,clinical characteristics,and prognosis of neonatal stroke in Shenzhen,China.Methods Led by Shenzhen Children's Hospital,the Shenzhen Neonatal Data Collaboration Network organized 21 institutions to collect 36 cases of neonatal stroke from January 2020 to December 2022.The incidence,clinical characteristics,treatment,and prognosis of neonatal stroke in Shenzhen were analyzed.Results The incidence rate of neonatal stroke in 21 hospitals from 2020 to 2022 was 1/15 137,1/6 060,and 1/7 704,respectively.Ischemic stroke accounted for 75%(27/36);boys accounted for 64%(23/36).Among the 36 neonates,31(86%)had disease onset within 3 days after birth,and 19(53%)had convulsion as the initial presentation.Cerebral MRI showed that 22 neonates(61%)had left cerebral infarction and 13(36%)had basal ganglia infarction.Magnetic resonance angiography was performed for 12 neonates,among whom 9(75%)had involvement of the middle cerebral artery.Electroencephalography was performed for 29 neonates,with sharp waves in 21 neonates(72%)and seizures in 10 neonates(34%).Symptomatic/supportive treatment varied across different hospitals.Neonatal Behavioral Neurological Assessment was performed for 12 neonates(33%,12/36),with a mean score of(32±4)points.The prognosis of 27 neonates was followed up to around 12 months of age,with 44%(12/27)of the neonates having a good prognosis.Conclusions Ischemic stroke is the main type of neonatal stroke,often with convulsions as the initial presentation,involvement of the middle cerebral artery,sharp waves on electroencephalography,and a relatively low neurodevelopment score.Symptomatic/supportive treatment is the main treatment method,and some neonates tend to have a poor prognosis.关键词
脑卒中/多中心研究/新生儿Key words
Stroke/Multicenter study/Neonate引用本文复制引用
时莉秀,陈诚,涂惠英,余章斌,黄进洁,曾淑娟,陈晚铃,刘颖,郭燕平,毛姣玉,李晓东,冯晋兴,张谦慎,谢治利,黄梅英,晏昆山,应尔雅,陈俊,王艳荣,刘亚萍,宋波,刘华艳,韦艳芳,肖晓冬,唐红,王宇娜,蔡茵莎,龙琦,许汉强,王会战,孙倩,韩芳,张瑞彪,路欣茹,杨传忠,窦蕾,时会菊,王瑞,蒋萍,深圳新生儿数据协作网,张雨茜,杨林颖,何胜男,陈佩娟,韩静..深圳市新生儿脑卒中多中心现况调查[J].中国当代儿科杂志,2024,26(5):450-455,6.基金项目
深圳市医疗卫生三名工程项目(No.SZSM202311027) (No.SZSM202311027)
广东省高水平医院建设经费(LCYJ2022091) (LCYJ2022091)
深圳市科技计划项目基础研究面上项目(JCYJ20220530155611026) (JCYJ20220530155611026)
广东省临床重点专科建设项目. ()