中国当代儿科杂志2024，Vol.26Issue(5)：486-492,7.DOI:10.7499/j.issn.1008-8830.2311146
难治性肺炎支原体肺炎患儿合并栓塞的危险因素分析及列线图预测模型的构建
Risk factors for embolism in children with refractory Mycoplasma pneumoniae pneumonia and construction of a nomogram model for prediction of embolism
谢利娜 1冯特 1郭燕军 1张玉会 1李远哲 1张万存1
作者信息
- 1. 郑州大学附属儿童医院儿科呼吸内科,河南郑州 450018
- 折叠
摘要
Abstract
Objective To study the risk factors for embolism in children with refractory Mycoplasma pneumoniae pneumonia(RMPP)and to construct a nomogram model for prediction of embolism.Methods This retrospective study included 175 children diagnosed with RMPP at Children's Hospital Affiliated to Zhengzhou University from January 2019 to October 2023.They were divided into two groups based on the presence of embolism:the embolism group(n=62)and the non-embolism group(n=113).Multivariate logistic regression analysis was used to screen for risk factors of embolism in children with RMPP,and the R software was applied to construct the nomogram model for prediction of embolism.Results Multivariate logistic regression analysis indicated that higher levels of D-dimer,interleukin-6(IL-6)and neutrophil to lymphocyte ratio(NLR),lung necrosis,and pleural effusion were risk factors for embolism in children with RMPP(P＜0.05).The area under the curve of the nomogram model for prediction of embolism constructed based on the aforementioned risk factors was 0.912(95％CI:0.871-0.952,P＜0.05).The Hosmer-Lemeshow goodness-of-fit test showed that the model had a good fit with the actual situation(P＜0.05).Calibration and decision curve analysis indicated that the model had high predictive efficacy and clinical applicability.Conclusions Higher levels of D-dimer,IL-6 and NLR,lung necrosis,and pleural effusion are risk factors for embolism in children with RMPP.The nomogram model based on these risk factors has high clinical value for predicting embolism in children with RMPP.关键词
难治性肺炎支原体肺炎/列线图/预测模型/危险因素/儿童Key words
Refractory Mycoplasma pneumoniae pneumonia/Nomogram/Predictive model/Risk factor/Child引用本文复制引用
谢利娜,冯特,郭燕军,张玉会,李远哲,张万存..难治性肺炎支原体肺炎患儿合并栓塞的危险因素分析及列线图预测模型的构建[J].中国当代儿科杂志,2024,26(5):486-492,7.
