四川省2022年入学新生结核分枝杆菌潜伏感染与肺结核患病情况分析OA北大核心CSTPCD
Analysis of latent tuberculosis infection and active pulmonary tuberculosis diprevalence among newly admitted students of Sichuan Province for the year 2022
目的:对2022年四川省入学新生结核病体检情况进行汇总和分析,了解全省入学新生结核分枝杆菌潜伏感染(latent tuberculosis infection,LTBI)与结核病患病情况,为学校新生入学结核病检查工作开展提供理论依据.方法:从四川省学籍管理系统中获得2022年全省各级各类学校入学新生基本信息,制作《2022年秋季新生入学结核病体检信息表》,建立数据库,采用描述性统计分析方法,分析新生入学结核病检查中结核病患者及LTBI者检出情况及其流行病学特征,追踪LTBI者接受预防性治疗及完成情况.结果:2022年四川省各级各类学校入学新生2 787 900名规范开展结核病体检,占全部新生的97.69％(2 787 900/2 853 817),发现活动性肺结核患者247例,检出率为8.86/10万(247/2 787 900).其中,女性患病率为10.11/10万(145/1 434 131),高于男性[7.18/10万(102/1 419 686)],差异有统计学意义(x2=7.058,P＜0.01).四川省1 790 830名入学新生开展了 LTBI检测,感染率为3.09％(55 313/1 790 830).符合预防性治疗条件的单纯结核菌素皮肤试验强阳性/重组结核分枝杆菌融合蛋白(EC)或γ-干扰素释放试验阳性者8104例中,13.73％(1113/8104)接受了预防性治疗,925例完成了全疗程,完成治疗率为83.11％,未完成治疗的新生中有2例在治疗期间转为活动性结核病.结论:四川省2022年入学新生体检率高,但LTBI检出率较低,接受预防性治疗率不高.
Objective:To understand the prevalence of latent tuberculosis infection(LTBI)and active pulmonary tuberculosis among newly admitted students in Sichuan Province in 2022,students'tuberculosis screening results were summarized and analyzed to provide theoretical basis for implementation of newly admitted student tuberculosis screening in schools.Methods:Basic information on newly admitted students in all types of schools in Sichuan Province for the year 2022 was obtained from the provincial educational enrollment system,and a database was established using"2022 Autumn Student Enrollment Tuberculosis Screening Information Form".Descriptive statistical analysis method was used to analyze the detection of tuberculosis and LTBI among newly admitted students,including their epidemiological characteristics and tracking result of LTBI cases taking and completing preventive treatment.Results:In 2022,a total of 2 787 900 newly admitted students in schools across Sichuan Province underwent standardized tuberculosis screening,accounting for 97.69％(2 787 900/2 853 817)of all newly admitted students.Active pulmonary tuberculosis was detected in 247 students,with a detection rate of 8.86/100 000(247/2 787 900).The prevalence among female was 10.11/100 000(145/1 434 131),higher than that among males which stood at 7.18/100 000(102/1 419 686),the difference was statistically significant(x2=7.058,P＜0.01).Among 1 790 830 new students tested for LTBI,the infection rate was 3.09％(55 313/1 790 830).Among the 8104 students eligible for preventive treatment,13.73％(1 113/8104)took such treatment,and 925 completed the whole course,resulting in an 83.11％completion rate,two of the new students who did not complete the treatment became active tuberculosis patients during the treatment period.Conclusion:In Sichuan Province in 2022,the screening rate for LTBI was high among newly admitted students,however,the detection rate of LTBI was relatively low,and the proportion of LTBI students receiving preventive treatment was not high.
夏岚;肖月;陈闯;夏勇;朱穗;张灵麟
四川省疾病预防控制中心结核病预防控制所,成都 610041暨南大学基础医学与公共卫生学院,广州 510632
临床医学
分枝杆菌,结核分枝杆菌感染学生数据说明,统计
Mycobacterium tuberculosisMycobacterium infectionsStudentsData interpretation,statistical
《中国防痨杂志》 2024 (006)
664-671 / 8
评论