中国临床药理学杂志2024，Vol.40Issue(11)：1654-1657,4.DOI:10.13699/j.cnki.1001-6821.2024.11.024
用于诊断生长抑素受体阳性神经内分泌肿瘤的新药——68 Ga-DOTATOC
68 Ga-DOTATOC,a new diagnostic agent for localization of somatostatin receptor positive neuroendocrine tumors
赵思邈 1陈超阳 1魏然 1张玄龄 1周颖2
作者信息
- 1. 北京大学第一医院药剂科,北京 100034
- 2. 北京大学第一医院药剂科,北京 100034||北京大学第一医院药物临床试验机构,北京 100034
- 折叠
摘要
Abstract
68Ga-DOTATOC injection is a radiopharmaceutical agent for positron emission tomography localization of somatostatin receptor positive neuroendocrine tumors(NETs)in adult and pediatric patients.68 Ga-DOTATOC binds to cells that express somatostatin receptors(SSTRs),including malignant neuroendocrine cells that overexpress SSTR2 receptor.Gallium-68 is a radionuclide used in positron emission tomography for tumor diagnosis.This paper introduces its the mechanism of action,pharmacokinetics,usage and dosage,clinical evaluation,safety and use in specific populations.关键词
68Ga-DOTATOC/放射性诊断剂/生长抑素受体阳性神经内分泌肿瘤Key words
68 Ga-DOTATOC/radiopharmaceutical agent/somatostatin receptor positive neuroendocrine tumor分类
医药卫生引用本文复制引用
赵思邈,陈超阳,魏然,张玄龄,周颖..用于诊断生长抑素受体阳性神经内分泌肿瘤的新药——68 Ga-DOTATOC[J].中国临床药理学杂志,2024,40(11):1654-1657,4.
