中国临床药理学杂志2024，Vol.40Issue(11)：1665-1669,5.DOI:10.13699/j.cnki.1001-6821.2024.11.027
mRNA疫苗在癌症和传染性疾病方面的研究现状
Research stauts of mRNA vaccines in cancer and infectious diseases
摘要
Abstract
With the advantages of high efficiency,safety,potential for rapid development,and cost-effectiveness,mRNA vaccines have become a powerful therapeutic platform for cancer and infectious diseases.The shortcomings of mRNA vaccines,such as instability and low in vivo delivery efficiency,have been effectively improved by structural modification of mRNA vaccines and delivery improvement.Based on the currently approved mRNA vaccines and clinical trials of mRNA vaccines,this paper reviews the classification,structural modification,mechanism of action,and applications of mRNA vaccines in cancer and infectious diseases,and discusses the current challenges and future development prospects of mRNA vaccines.关键词
mRNA疫苗/癌症/传染性疾病/递送系统Key words
mRNA vaccines/cancer/infectious diseases/delivery sys-tems分类
医药卫生引用本文复制引用
李灿,刘爽,张雪..mRNA疫苗在癌症和传染性疾病方面的研究现状[J].中国临床药理学杂志,2024,40(11):1665-1669,5.基金项目
佳木斯大学博士专项科研基金资助项目(JMSUZ2019-02) （JMSUZ2019-02）
