中国临床药理学杂志2024，Vol.40Issue(11)：1670-1674,5.DOI:10.13699/j.cnki.1001-6821.2024.11.028
缺氧诱导因子-1α在肿瘤中的病理机制及中药干预的研究现状
Pathological mechanism of hypoxia-inducible factor-1α in tumours and the current status of research on Chinese medicine intervention
摘要
Abstract
Traditional Chinese medicine can regulate the hypoxia-inducible factor-1α(HIF-1α)signalling pathway and slow down tumour progression mainly by inhibiting tumour angiogenesis,glycolysis,epithelial mesenchymal transition and other pathological processes.This paper,starting from HIF-1α and related factors,reviews its pathological mechanism in tumours and the research of traditional Chinese medicine interventions with the aim of providing theoretical references for the treatment of tumours with traditional Chinese medicine.关键词
中药/缺氧诱导因子-1α/肿瘤/缺氧Key words
Chinese medicine/hypoxia-inducible factor-1α/tumour/hypoxia分类
医药卫生引用本文复制引用
刘瑜,张志明,张利英,郝国雄,祁亚锋,徐倩,刘叶元,袁超,朱鹏,刘永琦..缺氧诱导因子-1α在肿瘤中的病理机制及中药干预的研究现状[J].中国临床药理学杂志,2024,40(11):1670-1674,5.基金项目
国家自然科学基金资助项目(82260882) （82260882）
高端人才承担省级科技计划基金("长江学者奖励计划")资助项目(22ZD1FA001) （"长江学者奖励计划"）
