中国临床药学杂志2024，Vol.33Issue(2)：87-93,7.DOI:10.19577/j.1007-4406.2024.02.002
不同等级和类型的医疗机构中成药超说明书用药现状调查
Investigation and analysis of off-label drug use of Chinese patent medicine in medical institutions of different levels
摘要
Abstract
AIM To investigate the current situation of off-label use of Chinese patent medicines(CPMs)in various medical institutions at all levels and analyze the causes,so as to promote the rational application of CPMs in clinical practice.METHODS A questionnaire on the off-label use of CPMs was designed using Questionnaire Star.A total of 42 valid questionnaires were obtained from 44 medical institutions of different levels and types.The off-label use of CPMs was analyzed from the following aspects:the phenomenon of off-label use of CPMs,management system,approval process,manifestation form of reflection after approval and filing,implementation of the system,follow-up analysis and prescription review.RESULTS The off-label use of CPMs was more common in high-grade and specialized medical institutions.The phenomenon of off-label use of CPMs in the medical institutions of traditional Chinese medicine series was more than that in the medical institutions of Western series and integrated Chinese and Western series.The medical institutions with high levels were better than the medical institutions with low levels in terms of management systems and approval processes.The medical institutions of the Western medicine series were superior to the medical institutions of the Chinese medicine series in terms of system implementation,prescription authorization,filing data review and tracking and analysis.CONCLUSION Improving the management system of off-label use of CPMs,strengthening authorization management of Chinese patent medicine prescriptions and tracking the clinical outcomes and adverse reactions of off-label use of CPMs are conducive to improving the current situation of off-label use of CPMs and improving the rational clinical application of CPMs.关键词
中成药/超说明书/管理制度/审批流程/知情同意/处方审核/处方点评Key words
Chinese patent medicine/off-label drug use/management system/approval process/informed consent/prescription audit/prescription evaluation引用本文复制引用
宋毅斐,杨文宝,王辉,张慧月..不同等级和类型的医疗机构中成药超说明书用药现状调查[J].中国临床药学杂志,2024,33(2):87-93,7.基金项目
山东省中医药科技项目(编号M-2022164) （编号M-2022164）
