中国内镜杂志2024，Vol.30Issue(5)：69-74,6.DOI:10.12235/E20230388
耳内镜下鼓膜修补术后穿孔再修补的疗效分析
Analysis of curative effect of re-repair of perforation after tympanic membrane repair under ear endoscope
王干 1陈志凌1
作者信息
- 1. 杭州市中医院 耳鼻咽喉科,浙江 杭州 310007
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of artificial dura mater and epidermal growth factor in the repair of tympanic membrane perforation after endoscopic tympanic membrane repair.Methods 58 patients with tympanic membrane perforation were randomly divided into two groups,29 cases in each.Group A was repaired with gelatin sponge,group B was repaired with artificial dura mater and epidermal growth factor.The tympanic membrane healing was reviewed every month,and the pure tone audiometry was reviewed after 3 months.Results The success rate of repair in group A was 34.48%(10/29),and that in group B was 75.86%(22/29).The difference was statistically significant(P<0.05).The air-bone gap in group A was improved by(7.32±2.68)dB HL,and that in group B was improved by(21.77±4.65)dB HL.The difference was statistically significant(P<0.05).Conclusion Artificial dura mater is a suitable tympanic membrane regeneration scaffold.Epidermal growth factor can promote the healing of tympanic membrane perforation.The combination of the two is a feasible treatment for tympanic membrane repair.关键词
鼓膜修补术后/鼓膜穿孔/耳内镜/再修补/人工硬脑膜/表皮生长因子Key words
tympanic membrane repair/tympanic membrane perforation/ear endoscope/re-repair/artificial dura mater/epidermal growth factor分类
医药卫生引用本文复制引用
王干,陈志凌..耳内镜下鼓膜修补术后穿孔再修补的疗效分析[J].中国内镜杂志,2024,30(5):69-74,6.
