中国脑血管病杂志2024，Vol.21Issue(5)：289-296,8.DOI:10.3969/j.issn.1672-5921.2024.05.001
基于计算机辅助半自动测量的颅内动脉瘤形态学参数与动脉瘤破裂相关性分析
Morphological risk factors for intracranial aneurysm rupture based on computer-assisted semi-automated measurements
摘要
Abstract
Objective To evaluate the correlation between 3D morphological parameters of aneurysms based on the computer-assisted semi-automated measurement and the risk of aneurysm rupture.Methods From October 2019 to October 2022,patients with ruptured multiple aneurysms admitted to the Department of Neurosurgery of Xuanwu Hospital,Capital Medical University were retrospectively included.Aneurysmal morphological parameters(including aneurysmal diameter,maximum diameter,width,neck width,volume,flow angle,parental artery diameter,surface area,wave index and non-spherical index)were measured by computer-assisted semi-automated measurement methods.The length-to-width ratio,wide-to-neck ratio,aspect ratio and size ratio were calculated,and the aneurysm location information was recorded.The ruptured aneurysms in multiple aneurysms were included in the ruptured group,and the remaining aneurysms were included in the unruptured group.Uni variable analysis and binary Logistic analysis were used to evaluate the differences in morphological parameters and location information between the ruptured and unruptured groups.Results All 56 patients with multiple ruptured aneurysms and a total of 126aneurysms were included in the group for analysis.Concerning morphology,including diameter＞5 mm(51.8％[29/56]vs.15.7％[11/70],P＜0.01),maximum diameter＞6mm(57.1％[32/56]vs.25.7％[18/70],P＜0.01),flow angle＞107°(57.1％[32/56]vs.35.7％[25/70],P=0.016),wide-to-neck ratio＞1.1(50.0％[28/56]vs.30.0％[21/70],P=0.022),aspect ratio＞1.1(46.4％[26/56]vs.25.7％[18/70],P=0.015)and size ratio＞1.9(57.1％[32/56]vs.10.0％[7/70],P＜0.01),there was significant difference between the ruptured and unruptured group;Concerning locations,aneurysms are mainly located in the posterior communicating segment of the internal carotid artery(39.3％[22/56])and the middle cerebral artery(23.2％[13/56])in ruptured group,while in the middle cerebral artery(28.6％[20/70])and the non-posterior communicating segment of internal carotid artery(27.1％[19/70])in unruptured group,and there was significant difference in distribution of aneurysm locations(P=0.003).Multivariate Logistic regression analysis showed that size ratio＞1.9 was an independent risk factor for aneurysm rupture(OR,11.62,95％CI 2.40-56.15;P=0.002).Concerning locations,posterior communicating artery aneurysms had a significantly higher risk of rupture compared with the non-posterior communicating segment of internal carotid artery(OR,19.25,95％CI 2.19-169.51;P=0.008).Conclusion For multiple intracranial aneurysms,the size ratio of the three-dimensional morphological parameters of aneurysms＞1.9 is an independent risk factor for aneurysm rupture,and the rupture risk of posterior communicating artery aneurysms is significantly higher than that of non-posterior communicating segment of internal carotid artery.关键词
颅内动脉瘤/计算机辅助半自动测量/形态学参数/位置/破裂动脉瘤Key words
Intracranial aneurysms/Computer-assisted semi-automated measurement/Morphological parameters/Location/Rupture aneurysms引用本文复制引用
王雅栋,耿介文,胡鹏,何川,张鸿祺..基于计算机辅助半自动测量的颅内动脉瘤形态学参数与动脉瘤破裂相关性分析[J].中国脑血管病杂志,2024,21(5):289-296,8.基金项目
北京市科学技术委员会首都临床诊疗技术研究及转化应用(Z201100005520021) （Z201100005520021）
北京市卫生健康科技成果和适宜技术推广项目(BHTPP202018) （BHTPP202018）
北京市博士后资助项目(2023-ZZ-009) （2023-ZZ-009）
