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中国高血压女性尿失禁及其亚型的危险因素:一项为期4年的前瞻性队列研究

尹嘉惠 庞海玉 刘静怡 朱兰 乔友林

中国实用妇科与产科杂志2024,Vol.40Issue(5):549-555,7.
中国实用妇科与产科杂志2024,Vol.40Issue(5):549-555,7.DOI:10.19538/j.fk2024050115

中国高血压女性尿失禁及其亚型的危险因素:一项为期4年的前瞻性队列研究

Risk factors for urinary incontinence and its subtypes in Chinese hypertensive women:a 4-year prospective cohort study

尹嘉惠 1庞海玉 2刘静怡 1朱兰 3乔友林1

作者信息

  • 1. 中国医学科学院北京协和医学院群医学及公共卫生学院,北京 100730
  • 2. 中国医学科学院北京协和医学院北京协和医院临床医学研究所转化医学国家重大科技基础设施预防与早期干预平台,北京 100730
  • 3. 中国医学科学院北京协和医学院北京协和医院妇产科国家妇产疾病临床医学研究中心,北京 100730
  • 折叠

摘要

Abstract

Objective To analyze the risk factors for new-onset urinary incontinence(UI)and its subtypes in hypertensive women.Methods The National Epidemiological Survey of Female Pelvic Floor Dysfunction adopted a multi-stage stratified cluster sampling method,inclusion criteria ≥20 years old and residing in the registered area for at least 5 years,and exclusion criteria being pregnancy or severe mental or physical illness.The cohort was surveyed at baseline between May 2014 and January 2016 and followed up between June and December 2018.Based on the survey data mentioned above,this study included women with hypertension at baseline,excluded women with UI or other pelvic floor disorders at baseline,and ultimately included 1183 hypertensive women.Poisson regression was used to assess the relationship between new-onset UI,stress urinary incontinence(SUI),urge urinary incontinence(UUI)and potential risk factors in hypertensive women.Results Risk factors for UI included age≥60 years(RR=1.60,95%CI 1.11-2.30),intermediate educational level(junior middle school:RR=1.68,95%CI 1.13-2.50;senior school:RR=1.70,95%CI 1.08-2.68),smoking(RR=1.86,95%CI 1.07-3.23),and high body mass index(BMI)(overweight:RR=1.90,95%CI 1.32-2.73;obesity:RR=2.31,95%CI 1.40-3.82).High BMI(overweight:RR=2.00,95%CI 1.27-3.16;obesity:RR=2.51,95%CI 1.33-4.73)was a risk factor for SUI.Hypertensive women over the age of 60 years(RR=3.20,95%CI 1.20-8.52)and in the rural areas(RR=2.65,95%CI 1.20-5.86)were prone to developing new-onset UUI.Hypertensive women with intermediate educational level(junior middle school:RR=3.26,95%CI 1.14-9.28;senior school:RR=3.81,95%CI 1.27-11.40)and postmenopausal hypertensive women(RR=3.79,95%CI 1.13-12.68)were susceptible to new-onset MUI.Conclusion Among hypertensive women,the risk factors for new-onset UI were advanced age,junior middle school and senior school education,high BMI,and smoking,for new-onset SUI were high BMI,and for new-onset UUI were advanced age and rural region,for new-onset MUI were junior middle school,senior school education and post meno pausal.

关键词

尿失禁/高血压/危险因素

Key words

urinary incontinence/hypertension/risk factor

分类

医药卫生

引用本文复制引用

尹嘉惠,庞海玉,刘静怡,朱兰,乔友林..中国高血压女性尿失禁及其亚型的危险因素:一项为期4年的前瞻性队列研究[J].中国实用妇科与产科杂志,2024,40(5):549-555,7.

基金项目

国家重点研发计划(2021YFC2701300) (2021YFC2701300)

国家自然科学基金(72104247) (72104247)

中央高水平医院临床科研业务费资助项目(2022-PUMCH-A-023) (2022-PUMCH-A-023)

中国实用妇科与产科杂志

OA北大核心CSTPCD

1005-2216

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